First off I would like to say that Tryndamere still is pwning after nerf.
He might even be better with his extra critical chance, because then he got room for another bloodthirster=even more pwnage.

I choose to only take critical damage runes because it will help ALOT in mid/late game as Tryndamere is critical hitting almost every hit. And this even give him a little bit of early game damage, but still be defensive at early game since he is really squishy.

I chose 22 offensive /8 defensive since its the only logical masteries build for the critical king of LoL.

I like to start off withand 2 health potions at the start. It helps alot with the extra critical chance in early game! This way tryndamere is going to be a BIG damage dealer even on early game, but unfortunately still squishy, so dont do any stupid dive.
At midgame you should have,and. When you have all those items you can start playing more offensive because you will crit as hell and have your ultimate.
Now at late game getand then just fill up the rest of your inventory with, now noone will have a chance against you.

I choose to max my(Q) spell first because this give me a great healing advantage + less cooldown on my healing spell, then I choose to max my(E) spell because this give me a great farming opportunity. But if I meet alot of AD champs I sometimes max my(W) spell because at level 5 it decreases nearby enemies AD by 100! it can help out ALOT in teamfights since it targets all nearby enemies. Its like an AOE exhaust!

is a ****ing lifesaver sometimes and also helps out alot if you meet an AD champion.

Well I just wanted to say that tryndamere is a ****ing beast and keep on playing him.
This guide might not been the best but should be pretty helpful+I made kind of a guide to him too. I havent slept anything either so somethings in the build might sound ******ed idk. Hope I helped someone anyway :).