Welcome to my guide, this is my first guide and I have a lot of experience with vayne, she is one of my favorite champs!

This guide is for people who bought Vayne for one reason: DESTROY ALL ENEMIES. This guide will be brief and to the point, with not to much strategy. More will be added over the course of my leisure! I'm lazy xD.

Enjoy!

Pros:

---

1: She is strong all game
2: Amazing Ulti.
3: Great assasin/escaper
4: A stealth! (useful even though short)
5: An AMAZING chasing ability! With passive and ulti and items!

Cons:

---

1: Squishy
2: Can be ganked fairly easily without flash/ultimate
3: Will be complained at for being op late game (not a con but it is funny.)

Vayne benefits from 3 main things: attack speed, crit, and attack damage. When you play her please make sure you realize she is extremely squishy and if you die a few to many times this build will have almost no success.

Runes:
AS, and Crit damage, WHY NO CRIT RUNES? Well, our items will get us to almost 100% crit as it is, so what do we do? Stack some AS and crit damage for a little more sexy damage. The MR runes are for added survival.

Itemization: Bear in mind that Zeal can be swapped out with sheen and used for extra damage with tumble. (I personally don't really like it over zeal considering the increase on attack speed and building into phantom dancer.)

Doran's Blade: Extra health and damage early game will help tremendously.

Berserker's Greaves: Extra movement and attack speed. (Even though Vayne is squishy and boots with tenacity would probably help a lot I prefer this to become more powerful early-mid game.)

Zeal: Why Zeal? Well... 1) It helps build phantom dancer
2) Movement speed, is great for chasing and getting away
3) Attack Speed for burst.
4) Delicious Crit.

Infinity Edge: If you get this from being fed the game is over for the enemy team. At this point you should have about 1.2-1.4 attack speed and be critting for 400-500. If you use your ult that can easily turn into 700. You now officially can begin nuking enemies.

Phantom Dancer: Oh how much this helps, the movement speed make it almost impossible to escape from you. I have chased people so fast with night hunter that I pass them and then condemn for a kill. The attack speed and crit destroys.

Blood Thirster: Congratulations if you made it this far you are doing well,
1) get bloodthirster for life steal and damage.
2) Chase enemies
3) Get kills
4) ?????
5) Profit!

The Black Cleaver: More nuke potential, can get a Frozen Malet or a Phage for some extra health instead if you want.

Alright here's the deal, after level 6 you should pick up an agility elixir whenever it runs out (only if you are farming well otherwise save up!) It will do a great job on these things:

1: It gives a great advantage on damage and is great for early game ganking with your deliciously awesome ultimate!
2: Farming is way easier.
3: CRIT!!!!

Picking this up can help you pick up those scared enemies who run with an extra shot or 2 from the elixir!

Goodbye to: /all lucky!

(quick note) Pick up ignite instead of ghost if you are having trouble picking up those pesky champs who escape! (Its a great spell for ranked!)

The summoner spells are purely for more chasing/escaping! They can be used to chase and get away. Use them well. Ignite and heal can be good for extra damage and survival if you would like. (personally I would stay away from heal!)

Why:

Flash: Best escaping spell in the game. It WILL save you many times! If you are new and do not have flash yet, pick up exhaust instead!

Ghost: Escaping and chasing: Great for a long term escape and pop this, with your ult, and even Master Yi won't escape. It's great fun.

Vayne is a relatively simple champ. Anyone can pick her up! (if you are trying to figure out if you should buy her, but don't know you'll like her, just try it if you have the IP it's well worth it)

Lets walk through her abilities:

Tumble (q) : One of the best chasing/escaping abilities in the whole game! It will add a bunch of damage to basics and is great for moving around the map with ease! Be careful and mana conscious with it early game. We don't want to have to use clarity as a summoner spell. Use it to chase whenever possible. In certain situations it may be beneficial in some escape situations to use the shot. (so it gets off cd faster) It requires timing and getting used to.

Silver bolts (w) : Always keep conscious of this as it can help you get the last hit on an enemy.

If you have 2 shots on an enemy and he has 100 health and is running, BUT your attacks only deal 50 damage no worries! You hit him and deal your 50 damage (Even if you have to tower dive for it) What happens? BAM! another 100 or so from silver bolts. Note: it deals true damage, it can't be resisted even a little bit! Congratulations you got the kill! This is how it should be used best!

Condemn (e) : Epic. This ability can change any team-fight in the jungle. Always hit them in a wall! It does some nice damage when you get the stun off. This will help you get a kill or save yourself! IF you are escaping use this to knock your opponent back if you are worried about your survival! This is one of the best anti melee spells in the game. It will save you if used right.

Final Hour (r) : Use it to chase. It will change a 1v1 if you use it at the appropriate time. Also use it well for the stealth=Almost guaranteed escape in jungle. Also use the stealth to gank out of bushes it will be the end of any enemy late game. The late game damage on this ability is borderline ridiculous. Use it well.

Thanks for reading my guide. If you cannot 2 shot enemies with this build, you're doing it wrong. Please give it a try! I appreciate any criticism! This build has given me great success!

-shouldercat

^thats my LoL name too.