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Runes:
+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+6 Armor
Spells:
Flash
Heal
Items
Ability Order
Night Hunter (PASSIVE)
Vayne Passive Ability
Threats & Synergies
Senna
Her extreme range and stack ability makes it possible for Vayne to die to her without even procing her passive based on how fed Senna is.
Gragas
Gragas' cc and the ability to use to his ult to knock enemies back into Vayne makes him the ideal teammate. The longer the enemies are near Vayne the more she can proc their passive unless they just die.
Gragas
Gragas' cc and the ability to use to his ult to knock enemies back into Vayne makes him the ideal teammate. The longer the enemies are near Vayne the more she can proc their passive unless they just die.
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