This build is focus a lot on attack damage , crit and health thats why i pick thoes items and runes.I don't take a lot of attack speed because Vayne don't need. Just go in and cause a lot of Damage.

AA = Auto-attack
CC = Crowd Control
FB = First Blood
AP = Ability Power
AD = Attack Damage
MD = Magic Damage
AS = Attack Speed
MS = Movement Speed
MR = Magic Resistance
ArPen = Armor Penetration
MPen = Magic Penetration
LS = Life Steal
SV = Spell Vamp
DPS = Damage per seconds aka Damage
MDPS = Strong spells; casters
CDR = Cooldown Reduction
OOM = Out of Mana
MP = Mana
HP = Health
MP Regen = Mana Regeneration per 5 seconds
HP Regen = Health Regeneration per 5 seconds

Pros: -> A lot of Damage
-> In my opinion best char for 1v1
-> Very good escaper
-> Maybe the best chasers in the game
-> Great Ambusher

Cons: -> Targeted first, because she cause the biggest damage
-> Running out of mana very fast
-> Weak against stuns
-> Not an AoE

I go with Greater Mark of Desolation and Greater Quintessence of Desolation because they help to increase your damage and make your early laning game very easy.
Then for seals I go with Greater Seal of Alacrity to improve your early laning game, and the increased attack speed helps Vayne for farm faster.
For glyphs i take Greater Glyph of Celerity for cooldown.

I take a 21/0/9 mastery on Vayne to increase her damage, and allow her to level up faster and it helps you to level very fast on mid.
I don't take defensive masteries cause Vayne have reduce survivability.

My items are ok for any situation but try to make changes according to the enemy team.
If the enemy team get a tank with a lot of hp try to makeMadred,s Bloodrazor to put him down faster.
Also if you don't need to much hp you can switch Frozen Mallet with aPhantom Dancer.
Try to make your own items and never follow exactly a build.
The best boots for Vayne because they give you movement speed and attack speed.
This item is very good cause it have a lot of Attack Damage and Life Steal.
Huge attack damage and critical strike...the passive is very useful.
Trinity Force is good because it give you a little from everything...and you have the passive for slow the enemy and the passive from Shen which deal a lot of damage after a skill is used.
This item is useful because it give us Attack Damage + Attack speed and Passive armor penetration.
Finally this item gives you Attack Damage + a lot of HEALTH which is good because Vayne don't have too much life.

Passvie - Gives huge amounts of movement speed when moving towards an enemy champion.
Tumble - She cast herself on the ground and her next attack will deal bonus damage
- This skill can be used as an escape option
Silver Bolts - This is a passive ability
- No Cost
- After you shot 2 arrows on the same target the 3rd arrow will deal bonus damage
Condemn - Is a high dammage arrow
- Push enemy traget away
- If the target is knock in a wall , the target get stunned for a short time
Final Hour - She get Bonus attack damage
- Bonus Movement speed if she is near enemy champion
- She get stealth for 1,5 sec when use Tumble

For summoner Spells i takeGhost andFlash for a better survivability and for catch enemy more easy.
If you don't like one of these spells you can also take Ignite for faster kills in early game.It's alright I guess. It does some true damage but not much more than that. Unless you're going against champions such as warwick, mundo, swain etc this is just a true damage damage over time spell, unlike Exhaust which does so much more than just add a few hundred more damage to the fight.
Also you can use exhaust. It's an extra slow for ganking as well as reducing the enemy armor and magic resistance with the masteries. Late game it almost negates an enemy champion's damage completely for 3.5 seconds. An incredibly versatile spell.
Teleport.Great if you're going solo top. You'll be able to gank freely and then quickly getting back to defend top lane. Teleport also makes it able to sneak up on people by teleporting to a nearby ward in some bushes.

I will be adding much more to this guide and if you consider it great please vote +1