Welcome to my first Guide on Mobafire... well i started playing vayne right after she came out and played here the whole time. I didnt loose with her yet so i think that this build actually does work ;)

try to harass with q right at lvl 1, on lvl 2 try to hit enemy to a wall with ur e spell. When u get to lvl 3 you will be doin massive dmg if u can get the 3 stacks on your enemy. If needed use ghost/flash do land them and to maybe get firstblood. In mid/lategame get in the fight with from behind and clean it up :) and i dont need to explain 1v1 cuz shes just op... just run if u get an exhaust :)

cuz mobafire is slow with skills here the sequence: q-e-w-q-e-r-q-e-q-e-r-q-e-w-w-r-w-w

explanation:

passive: if u have an enemy in front of you, you run 40% faster.

q: ur bread and butter and "I'm a ****in ninja" skill. skillshot roll and adds an % amount of your ad (75% on lvl 5) on your next autoattack.

w: passive. stacks on your enemy. if u got 3 stacks on him it will do 4% of his max life as dmg. but if you shoot another target before u got 3 stacks on 1, ur stacks will dissapear on the old target.

e: knockback. if u hit the enemy into a wall there will be a stun. poppys e skill with range :).

r: has effect on your passive,q and attack dmg. q will stealth you 4 sec, ur passive makes u even faster and u get 55 attack dmg on lvl 1 for example.

well i even pwnd with her when i was totally drunk :D but the games took longer^^