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She loses to people who can get in her face and outdamage her at levels 1-2.
When you EQ onto her she most likely will retaliate with an E + Q or W, but that doesn't change the fact that she just took massive amounts of harass.
You can rinse repeat this when able to and eventually you can just all-in her. Having one disengage spell doesn't change anything.
2) Most top Mobafire guides explain how to play a champ and what he/she is good against. Reversely, you can conclude what they're not good against.
3) Elise also has bad farming with natural attacks. Thus, good sustained pushers will force her to go into spider form to cs effectively, giving these pushers - specially the melee ones - the chance to harass her more.