So I haven't seen Twitch in like 30 games (I've seen more Corki than this rat, actually) and suddenly he's in every single game as of yesterday. Not sure if I'm being messed with by random chance or if he's suddenly FOTM, but might as well throw some quick numbers out there for people wondering why he does a billion damage in lane. (Going to ignore levels past 9 as that is no longer early game).
  • Deadly Venom: Twitch's basic attacks debuff the target with poison, dealing 12 true damage over 6 seconds, stacking up to 6 times to deal 72 true damage total. This damage doubles once Twitch reaches level 6.

12 extra true damage per hit until he hits level 6 already seems pretty bad, but that's not all; just having the Deadly Venom debuff on you is extremely bad, because every auto/ Venom Cask will refresh the poison in addition to increasing stacks. So let's say you have 3 stacks on you and it's about to run out, but Twitch throws another autoattack at you. BAM! You now are poisoned yet again for another 6 seconds and will take the full 48 true damage from the DoT, even though he only attacked you once.

Being debuffed by Deadly Venom stacks in lane is almost as bad as being tagged with Mark of the Storm, as the only real way to deal with the mark is to stay out of range until the poison wears off, causing you to lose valuable CS in the process. Trading with Twitch thus feels extremely difficult for a most AD Carries unless your support can heal/shield and his cannot (which really should not happen).
  • Expunge: Deals 20 / 35 / 50 / 65 / 80 physical damage to all nearby enemies affected by Deadly Venom. Expunge deals an additional 15 / 20 / 25 / 30 / 35 (+0.2 per ability power) (+0.25 per bonus attack damage) damage for each stack of Deadly Venom that is active on the target, for a maximum of 130 / 170 / 210 / 250 / 290 (+1.2 per ability power) (+1.5 per bonus attack damage) damage with full stacks.

This is a terrifying amount of hurt; because autoattacks apply stacks of his passive, every auto Twitch lands basically deals 21 extra damage (15 + 24 * 0.25). Fortunately Twitch has no real "nuke" like Piltover Peacemaker, but Expunge is 1200 range and not a skillshot. Avoiding its damage means you have to be out of Twitch's autoattack range, making it very easy for a good Twitch to zone you out just by existing. If his support started lane with 2 pinks, then you generally can't do anything but pray and have your jungler camp bot to defend.

How do you guys generally handle a Twitch lane without having Thresh/ Nami or Caitlyn? I'd love to hear some feedback.