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So what I do is just spam my E button as I chase the enemy while constantly right clicking them, this usually maximizes auto attack and makes sure your Es are being spammed on cooldown
With full items (Rylai, Void, Rab, Liandry, Seraph) Hextech Gunblade and Taste of Blood healed in average 190 hp on hit (Q+E). And that's Raveneous hunter was not in place (can't have 5 bots in practice tool).
And as a bonus Gunblade helps to kite and chase enemies.
I have noticed that not many people pick her though, is she really that bad in this stage of the game? Or just the difficulty (because, let's be honest, she's hard to handle) is just too much for the players? Too bad we don't see her in games anymore because she's lovely.
Your guide is helping a lot too, although it seems a bit too much defensive which maybe is a good thing to not cause flame in your team for playing recklessly. :D
And just like you said, she is hard to play, which means you could get similar results with an easier to play champ like ahri for example.
You are right, I do play cassiopeia a little more defensively, but thats mostly in solo queue. When I play with my friends, I play much more aggressively, because I know that if I mess up and fall behind, they will carry me to my late game spike