Alright... I know, he's purely offensive, but offense can be the best defense at times, and especially when you run a guerrilla war-fare tactics upon your foes. >:)

Also, the other Pantheon is if you want more Mana... and is defensive a bit too, and your AD increases with more Mana, etc... can be quite good with that build per se, or it's an idea to try out as well, always try something new with Pantheon... :X

In this Guide, I will be short, and quick upon it, since I don't think anyone really likes to read lengthy paragraphs and such...

The Runes... well, I'm not entirely that smart upon Runes. Just think the extra defensive ones and Armor Penetration would be useful for Pantheon, for either Build.

There are many ways you can do the Masteries but I would think this be good, reason why... you can kill better and if the chance during your little killing frenzy or hunt, and you get ganked, just got that little bonus of Health, Armor, and Resistance to help you live just a little bit longer.

The Second Pantheon Build is for a more defensive Pantheon, or least, my new version and is alright... just hope you like getting more assists than kills. :P And get extra money from killing Champions, or with your assists, and extra money is ALWAYS good... till you have bought everything you need. And be helpful against Towers for your "weaker" team mates, if they have weak AD is what I mean by the way.

Pure Offense is the way to kill people. Pantheon is tagged as an Assassin, so why not make him like one? All the items increase his AD and AS, some give bonuses that are quite helpful.

First, you need them Boots of Speed and 3 Health Potions... will help out quite a lot.
And then you just follow the order of items... there are other ways of making a good Pantheon for sure, but thus far... this Item Setup has helped me out just as much as others, so it isn't too shabby.

Or you can try the Defense way, who knows... might do better in the long run, just don't get killed nor be a imbecile.

Spear Shot is a must to max out first, then aim for Heartseeker Strike, but of course as always... make sure you get your Ultimate, Grand Skyfall when you can. Aegis of Zeonia you don't need to max out right away, since it doesn't get bonuses from your AD, unlike the other two.

Just use Exhaust to slow your foes down so you can take them out before they get away, and for Ghost, that is good for chasing after Champions or for running away if you ever need to.

Well, for either Build you are there to kill in the end. If you go Offensive, you will kill your foes a lot faster, but then again... that Defensive build, all you really need to do is try not to get killed, your AD could get really high if you are really good with Pantheon. Maybe some items on either build could be sacrificed for the other, but... I think that might be a bit like all the other Builds, and sure mine isn't ENTIRELY unique either. Hope this helps or is useful to some people at least, and leave negative critiques off of this, just put a Vote if it doesn't work for you or if it does. Trying things out is part of being a gamer.

I will add on or change this Build when I need to or can.