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Diana Build Guide by Killerphotos
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Again same thing with my masteries, flat out AP with points in magic and armor penetration and magic resist and armor durability. I lend the extra point in the defense tree to the armor cause once you start dealing damage and racking up kills as the assassin in your team, the tanks start to get frustrated and tend to target you, but thats a good thing ;)
Diana is an annoying champion when you VS her, so put that annoyingness to use when you lane with her. By starting your skills with crescent strike and getting her shield at lvl 2 and her slow at lvl 3 you have already set yourself up for some pretty massive burst damage even as a solo if your solo laning. Stay out of range of stuns and grabs by spamming crescent strike, if you don't have a jungler than having your team help you get blue buff is an easy way to get early cooldown reduction and mana regen.