Master Yi

All 160+ champions are threats. With this build your own laner might be the biggest threat if they don't understand this is not a typical Vayne build and requires its first time before the game is over to truly start pressuring, damaging, disrupting, and finishing off its support item. Most enemy laners will notice the lack in early power, and Vayne's ability to trade because of her kit. Vayne can still disrupt engages, shred tanks, and keep your ADC alive, still if the enemy makes bad plays.... it will be in Vayne.