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Phage into Frozen Mallet takes advantage of Urchin Strike's on-hit capability and gives some survivability in the form of health, some damage, and a convenient slow effect so chasing shouldn't really be a problem most of the time.
From there, Sheen gives some nice burst and builds into Trinity Force to keep them from being able to itemize too heavily toward Armor or MR, not to mention extra health and mana, crit chance and move speed.
After that it really doesn't matter too much, but AP will enhance your Shark and Magic Pen will keep your DoT and your Shark from losing power.