Hello Mobafire community and welcome to my Hybrid Twisted Fate guide. This champion is rather underrated both in normal and ranked games and I think i should be fixed. Why? At least because he is very interesting champion which can be built in different ways.
(I'm sorry for possible mistakes - english is not my native language).

Marks

For marks I use Armor penetration - an obvious choice for AD carries.

Seals

For seals i use Flat Armor which is also pretty obvious. You need defense playing with any champion because "Dead champion doesn't do damage" (c)

Glyphs

For Glyphs i use Magic resist/lvl For comment watch "Seals"

Quintessences

Feel free to use either Armor Penetration or Attack Damage quintessences. Both of them are great.

21/9/0 is standart AD carry build and fits better then any other for Hybrid TF.

Start with boots and 3 hp potions. Wit's End and Ionic Spark are your core items. After that you can buy other items in any order you wish. Watch on enemy team build.
Lots of armor => The Black Cleaver
Lots of health => Madred's Blodrazor.

Skill Sequence is pretty standard for any AD Twisted Fate build and, actually, the only possible.

Teleport will help you in pushing lanes, banking, taking part in teamfights.
Flash is great escape SS which is also one of the best in entire game.

Pros

Mixed type of damage => hardly countered
Mana independent
Great sustain damage

Cons

Squishy
Low moment speed
Has not built-in escapes

I hope this guide will at least help you to enjoy playing with Twisted Fate. I don't think this build can be used in ranked games but i'm sure it will give you lots of fun in normals.
Enjoy!