Hello, This should be a short guide to how to use Lee Sin effectively. Read it all (it's not long) for the best results.

To Start out you can easily use him with out runes and the 9 utility masteries.

In the beginning of the match you want a early point in sonic wave just to heckle your opponents. don't use RS (resonating strike) just yet, because you don't have much health. after you get warmog's armor you should be able to take damage and stay in battle longer. remember Lee Sin's passive ability, every ability Lee Sin uses, the next two attacks have 50% increased attack speed. this means you can have 14 attacks in a row that all have increased attack speed.
it should look something like this:

Safeguard, two basics
Iron Will, two basics
Sonic Wave, two basics (if possible, if not go strait to resonating strike)
Resonating Strike, two basics
Tempest, two basics
Cripple, two basics
Dragon's Rage, two basics (if there not dead by then)

Pretty simple. Flat armor penetration marks, flat armor seals, flat attack speed glyphs, and armor and magic resist quints.

I always start out with Sonic Wave. then Tempest, then safeguard. maxing Tempest as soon as possible. Then Sonic Wave, Then safeguard. Getting your ultimate as soon as possible.

You should play as a huge team player. Very important that you don't go rushing in, have a tank start the fight then you go in and deal all the damage you possibly can. It's possible to jungle with this build but you must lane at the beginning, or at least until you get your life steal items.

Whats cool about Lee Sin is that, he really has 7 abilities. You can really use this to your advantage. At early levels you want to use sonic wave to heckle the enemy, but don't use resonating strike just yet, because you're very squishy until you get Warmog's Armor. That's why i get sonic wave as my first ability.