This build for Kayle is meant for an end-game player since the items take a long amount of time to farm gold for. But once Kayle is Level 18 with this complete set she will have no problem taking on 4 opponents at the same time, soloing turrets, and taking out half of the Baron's health.

I personally don't use runes yet but this is what I would hope to be a good rune guide for this build.

Pros

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Great tanker: She can kill enemies in a matter of seconds
Insane PK: Kayle does more than 500 damage on opponents with crit damage on basically every attack.
Life Leeching: With a crazy amount of attack speed, Kayle is able to life leech with almost every attack.
Movement: This build brings Kayle's speed to her limits and allows her to speed through terrain as well as rush to the aid of her team and their base.

Cons

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No armor: This build requires that Kayle doesn't purchase any armor increasing items. This makes it hard for her to withstand too many attacks.