Void Ooze + Bio-Arcane Barrage : Splendid to kill enemies
Caustic Spittle: Can be used for 1v1 (close combat) nice passive
Living Artillery: Used for KS :D and HARASS

Greater Mark of Desolation (Armor Penetration): Obvious...
Greater Seal of Alacrity (Attack Speed): Stronger Bio-Arcane Barrage
Greater Seal of Glyph (Attack Speed): Stronger Bio-Arcane Barrage
Greater Quintessence of Alacrity (Attack Speed): Stronger Bio-Arcane Barrage

1. First of all start of with a doran's blade. The hp can be crucial in fights
2. Second thing do is movement speed
3. Mana regen isn't required don't spam and use Bio-Arcane Barrage (W) alot
4. Madreds bloodrazor is killing with the ability of Bio-Arcane Barrage
5. Frozen Mallet slows EPIKNESS with the great of Kog'Maw it's easy to target
6. Movement speed and attack speed is crucial to make W perfect
7. Blood thurster surival ability (life steal) and damage :D
8. Infinite edge DAMAGE, CRIT CHANCE, GOOD PASSIVE
9. Sell your boot of mobility and buy all pots and oracle for a terrifying aura :D
10. Don't forget to buy your boots back!

Blocking Khartus Ulti! And other spells :D once in a while!

Takes out nasty nukers! (Ryze, Veigar, Lux)

Takes out nasty dodgers! (Teemo, Jax)

Nice heal and attack speed.