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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.11
9.3
19
Votes
1
LoL Champion Aurelion Sol Build Guide
LoL Champion Aurelion Sol Build Guide

[Patch 25.11] Master OTP Season 15 Aurelion Sol Guide (+ Matchups Detail)

Guide by Event Horizon updated June 1, 2025
  • In-depth
9.2
33
Votes
8
LoL Champion Kai'Sa Build Guide
LoL Champion Kai'Sa Build Guide

[25.11] LOADING SCREEN AP MID POKE KAISA GUIDE protein shakes are food

Guide by PalestinianLuck updated June 3, 2025
  • In-depth
9.2
13
Votes
0
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.11] Victorious Twisted Fate Guide for Season 15 | Jammed

Guide by Jammed updated May 31, 2025
  • In-depth
  • Featured
9.2
208
Votes
22
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.11] PrestigeGalaxy's 5M+ Mastery Guide to Katarina! 🗡️

Guide by PrestigeGalaxy updated May 28, 2025
  • In-depth
8.9
646
Votes
51
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

👉 🧊[ NEW SEASON 15 ] - Master's Guide to Midlane ANIVIA! S TIER PICK! 🧊 👈

Guide by RezoneVerified updated June 3, 2025
  • In-depth
  • Stream
8.9
37
Votes
4
LoL Champion Kled Build Guide
LoL Champion Kled Build Guide

MID Kled, the League of Legends' Don Quixote

Guide by Baion updated June 2, 2025
8.9
88
Votes
12
LoL Champion Lulu Build Guide
LoL Champion Lulu Build Guide

MID Lulu, the Psychopath Yordle

Guide by Baion updated June 2, 2025
8.9
70
Votes
9
LoL Champion Nasus Build Guide
LoL Champion Nasus Build Guide

[25.11] Nasus Mid OTP - Simplest In-Depth Guide S2025

Guide by SurferKiller updated May 29, 2025
  • In-depth
  • Stream
8.9
602
Votes
35
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

[Season 15] BodyThoseFools' Challenger Azir Guide [In-depth] (10,000,000+ Mastery Points) (Beat Faker)

Guide by Body Those Fools updated May 29, 2025
  • In-depth
8.7
256
Votes
38
LoL Champion Swain Build Guide
LoL Champion Swain Build Guide

MID/TOP Swain, the Ruthless Crow General

Guide by Baion updated June 2, 2025
8.7
23
Votes
4
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

15.11 My Potential is Limitless

Guide by Demonsedge90 updated May 29, 2025
  • In-depth
8.6
479
Votes
39
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

⚡ [SEASON 15 UPDATED!! ] Master Tier Midlane Orianna! THE BALLS HURT ⚡

Guide by RezoneVerified updated June 3, 2025
  • In-depth
  • Stream
8.6
275
Votes
25
LoL Champion Cho'Gath Build Guide
LoL Champion Cho'Gath Build Guide

[Season 14] Sakuritou Challenger Rank 1 Cho'Gath World Guide

Guide by Sakuritou updated June 3, 2025
  • In-depth
8.6
311
Votes
25
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[Patch 25.11] Hwei Season 15 Guide By Azzapp [Mid/APC/Sup]

Guide by Azzapp updated June 3, 2025
  • Stream
8.5
14
Votes
2
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.10] Zoe Ultimate Matchup Guide

Guide by AnxialSociety updated May 28, 2025
  • In-depth
8.3
22
Votes
5
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

25.11 Orianna

Guide by SeMike updated May 29, 2025
  • In-depth
8.3
525
Votes
68
LoL Champion Swain Build Guide
LoL Champion Swain Build Guide

[ Patch 25.11 NEW SEASON 15 UPDATED!! ] - SWAIN is the GOD OF MIDLANE PAIN! - 🤯

Guide by RezoneVerified updated May 30, 2025
  • In-depth
  • Stream
8.3
66
Votes
9
LoL Champion Zeri Build Guide
LoL Champion Zeri Build Guide

[25.S1.10] Lethality Burst Zeri Mid/Bot Season 15

Guide by RealLrd34 updated May 28, 2025
  • Off-Meta
8.1
6
Votes
0
LoL Champion Samira Build Guide
LoL Champion Samira Build Guide

[25.11] King Branco's Samira MID LANE Guide - Ultimate Guide From A Samira Mid OTP

Guide by KingBranco updated June 3, 2025
  • In-depth
8
13
Votes
3
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Vlad 15.10+ Item Guide

Guide by KormitLeFrag updated May 31, 2025
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYuumiZacZedZeriZiggsZileanZoeZyra
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