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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.13
New Guide
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.13] EUW Challenger Zoe OTP Guide

Guide by Kolashiu updated July 1, 2025
  • In-depth
New Guide
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

Season 15, Ult. Haste Twisted Fate | Always Around

Guide by ChessScholar updated June 29, 2025
6.3
6
Votes
4
LoL Champion Mel Build Guide
LoL Champion Mel Build Guide

[S15] Arcane AP Mid/Bot ♡

Guide by millysenpai updated June 29, 2025
  • In-depth
New Guide
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

(25.13)The Veigar Guide ALL Matchups İncluded(Only Guide You will Ever Need)

Guide by The Veigar updated June 29, 2025
  • In-depth
Rating Pending
LoL Champion Naafiri Build Guide
LoL Champion Naafiri Build Guide

[25.S1.10] Naafiri Mid/Jungle Guide Best Builds

Guide by Marex_je_u_bushu updated June 28, 2025
4.9
11
Votes
15
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[Season 14] Sakuritou Challenger Katarina Guide

Guide by Sakuritou updated June 29, 2025
2025, Season 2 Guides // Patch 25.12
9.8
586
Votes
34
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 15] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated June 25, 2025
  • In-depth
9.8
343
Votes
12
LoL Champion Kayle Build Guide
LoL Champion Kayle Build Guide

Rank 1 EUNE Top 8 EUW I Season 15 Kayle Guide by DesperateNasus Multi-season Challenger

Guide by Desperate Nasus updated June 24, 2025
  • In-depth
9.8
579
Votes
87
LoL Champion Aatrox Build Guide
LoL Champion Aatrox Build Guide

[15.12] Aatrox Mega Guide 7m MP Master Top 100 worldwide

Guide by Veng Shotz updated June 20, 2025
  • In-depth
9.8
831
Votes
54
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.12] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated June 20, 2025
  • In-depth
9.8
368
Votes
49
LoL Champion Sylas Build Guide
LoL Champion Sylas Build Guide

[25.12]✨ OTP Sylas MID Guide

Guide by angeLoon updated June 13, 2025
9.8
986
Votes
75
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

(25.11) Eriosun's Master Tier Complete Irelia Guide - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
9.5
165
Votes
8
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

Anguishs GrandMasters Akali Mid/Top S15 Guide Patch [15.12] - Every Matchup/Item/Rune explained!

Guide by Anguish333 updated June 16, 2025
  • In-depth
9.5
190
Votes
17
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.12] clipbot's Zoe guide for beginners

Guide by Aegox updated June 12, 2025
  • In-depth
9.2
410
Votes
43
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

(25.11) Eriosun's Complete Master Katarina Guide - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
9.2
1981
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.12] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated June 12, 2025
8.9
266
Votes
47
LoL Champion Ekko Build Guide
LoL Champion Ekko Build Guide

Power leon's guide for ekko players in mid lane

Guide by leonidas44 updated June 21, 2025
8.9
90
Votes
11
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

(25.11) Eriosun's Qiyana Midlane Master Tier Guide, Rank 1 on the 24 Sisters - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
8.9
602
Votes
35
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

[Season 15] BodyThoseFools' Challenger Azir Guide [In-depth] (10,000,000+ Mastery Points) (Beat Faker)

Guide by Body Those Fools updated June 11, 2025
  • In-depth
8.7
33
Votes
10
LoL Champion Kai'Sa Build Guide
LoL Champion Kai'Sa Build Guide

[25.12] LOADING SCREEN AP MID POKE KAISA GUIDE protein shakes are food

Guide by PalestinianLuck updated June 14, 2025
  • In-depth
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League of Legends Champions:

AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide