Greetings, fellow Mundo admirer, this is not a guide for the weak of heart. Instead it is a guide dedicated to the most amazing medic in the game, Dr. Mundo.

If you play Mundo casually, get the **** out.
If you play Mundo badly, get the **** out.
If you play Mundo but do not have a shrine dedicated to him, there is a guide in the link below.

http://www.wikihow.com/Build-a-Shrine-to-Your-Favourite-Celebrity

Now that we have the formalities out of the way. Lets recall Mundo's past with a little added flare.

It is said that the man now known as Dr. Mundo was born without any sort of syringes to stick into his back. Instead, he had an unquenchable desire to inflict pain through the lecture of Freudian theories (Especially that one with the mother lovin', that **** ain't cool man). By the time he was five, most of the pets in the Zaun neighborhood where Mundo grew up had gone fishing (No animals were harmed in the making of this guide, but I did chase off a few Jehovah Witnesses naked while making this guide). By his teenage years, his parents were in Mexico drinking water contaminated with hepatitis, because at the time Singed was working as a bartender in order to pay his college fees. By the time he had legally acquired his license to practice farming, he decided to become a doctor instead. His dad always told him that farming and medicine are two very different things. Mundo didn't understand and decided to ask Snoop Dog for advice.

Snoop Doggy Dogg I'm at home, layin low Everything is everything watin on my hoe I know its hard to imagne yet a nigga on my status Had a night like tonight look here I'm glad Came to an end My girlfriend slid into the bedroom with a women Come in, is what she said closed the door and jumped in the bed Baby would of gave a nigga head insted of flippin and trippin I run along with the PG, hm and that's on DP I mean what could I say, what could I do Anything I say and do is a catch 22 and I knew I had a clue I wasnt really trippin Of some type of suspion Tuesday night when I see you up a peanuts fishin' At first I wasn't gonna go dippin Then I said dame look at all these *****es Snatch up four fly *****es, time to ride I went inside couldnt believe my eyes Ridin at the highway, thangs going my way Tell by the earl pull the Bently in front Hit me with a G thang, **** a blunt Tell the *****es that be goin to my place Fellin like Teddy Pendagrass on the freeway Get my ****ed knocked off, in a G way Yea they know the program its a set and lovin each other and lovin my **** It's a trip but I don't see nothin wrong with it

That song was called Head Doctor, even though there is no brain surgery there is a fair amount of medical advice which I think Mundo took to heart.

Dr. Mundo has become equal parts serial killer and mad scientist, though no one is entirely sure how his butchery qualifies as science. They don't need to know, after all, Mundo is a wrestler, a bodybuilder a doctor and even a businessman all in one. However, he has made tremendous strides in mapping the pain response in the human brain by watching 16 and pregnant and shortly afterwards suffering severe brain damage and physical injury. Luckily he recovered, (from the physical damage, not the brain damage. Remember kids, once you watch 16 and pregnant, you're mentally ******ed) He has also tapped into the primal parts of the brain through chemistry, learning how to enhance aggression and adrenaline, as well as dulling conscience and the survival instinct (Then he perfected it because Mundo never dies). In short, Dr. Mundo's life's work has been how to create the perfect science-enhanced killer. Unfortunately, the city-state of Noxus regards such behavior as a sign of initiative and ambition, rather than inhumanity. Originally fighting for Zaun, Dr. Mundo was recruited to also fight for Noxus in the League of Legends; the Madman dual faction status represents the fruits of a blossoming relationship between Zaun and Noxus. He continues his experiments to this day, even using himself as an experimental subject, as evidenced by his disfigured appearance and his intelligent manner of speaking. There are rumors that the High Command in Noxus has given him free reign to pursue his life's work in his spare time.

Beware the Madman of Zaun. In his eyes, you are already dead.

This part is simple, you are the **********ing Mundo. You run around, throwing cleavers (or briefcases) at your enemies and rip your pants like the incredible hulk. Luckily when you do rip your pants, the game conveniently blurs it out with Kog Maw's face. This disappointed me greatly, why can't we see Mundo's throbbing member? Why is Kog Maw stealing the spotlight? Where the **** did I put my iPhone charger?

These questions are of course completely relevant and will be explained later.

Greater Quintessence of Regeneration
I shouldn't even have to explain this ****, Mundo is built off of regeneration, without regeneration you're just a Bologna sandwich without the mustard. Except replace mustard with survivability and coat it with cocaine...sweet sweet cocaine... The regeneration is perfect for teamfights, also very good for getting blue buff, which you always need as tank Mundo, no exceptions.

Greater Glyph of Warding
This may not always seem useful right? I mean, what if you are against a full AD team?
I'll tell you what you do, you get blue buff and tank as many Annie's as you can, do not worry if you see more than one Annie. Many people have told me that the other Annie is usually on my team when I have asked. Unfortunately I get a lot of bad people in games, this Annie is NOT on your team. Instead she is hacking, and as a countermeasure you must always steal her buffs and lure the enemy to her.
Chances are that you are going against a team with at least a little bit of AP, if not then you should be able to eliminate them easily with a Thornmail.

Greater Seal of Vigor
More health regen, always a must for a Mundo tank. After all, when someone slices off your ****, how are you going to make peanut butter sandwiches in the morning? Answer: You grow a new ******* and buy the crunchy kind.
Of course you are welcome to get dodge if you want to keep things fresh without the use of a Febreeze air freshener.
I learned that Febreeze doesn't always solve your problems, I thought I could make people smell better and be happier so I ran around a carnival once with a bottle of Febreeze and sprayed children in their eyes, that way they rub their eyes and touch other things, thus spreading the effect of cleanliness and ridding the world of rapists effectively.
This did not work and instead I was in a lot of trouble.

Greater Mark of Focus
This is a handy little thing to have because it allows you to pull more cleavers out of your *** and throw them at the enemy. I thought that the same would work if I threw my wifes wedding ring at the lions in the zoo, I was disappointed to see that it did not. It's alright though, my wife told me that she didn't mind because she never wanted the ring in the first place. Then she left and took my cat and mixed up my purse with hers. I think when she gets back i'll take out the garbage, she might be jealous and think that I love the lion more than her, but I wouldn't do that sort of thing anymore.

I choose to go into fortify because when the minions are up in your grill, you can drop it like its hot and splash damage the **** out of those minions, they'll drop like you just capped them with a 9mm.

Of course, I go into the damage tree afterwards because theres nothing left for me in the Defensive tree, I also like to keep some crit with me in those tricky situations. Like when you need to steal blue buff from your allies.

The items are obviously a great choice for any tank, but if you feel like being creative you can modify them to be good against a more AD or AP team, its your choice. Just like voting, I used to think that if you didn't vote the FBI would come to your house and steal all your illegal things like pornography, comic books and handheld guides on taxidermy.

Pros:

Good chaser (For those tricky fast ones like Kog Maw)
Good farmer (Because Mundo got a degree in farming)
Lots of HP and the magic resist and armor to back it up.
If you feel like jungling at the beginning instead of laning you can get away with it as long as you get a dorans ring.

Cons:

Fat girls will love you too much and as a result you'll have to cleave them in the face
Mundo cannot fly if you stack movement speed (i've tried)
Very squishy early game, you will get poked. Try to harass with cleavers and don't rush for kills otherwise you'll get insulted by weird spanish people. It keeps happening I don't know why.

Decide why you're interested in farming. It's hard work, and the industry is, for the most part, steeped in tradition (i.e. newcomers aren't exactly welcomed with open arms). If you've never farmed a day in your life, you're going to get a lot of raised eyebrows from farmers and non-farmers alike. Be ready to answer the question "Why do you want to farm?" with confidence.

Choose what kind of farming you'd like to do. There are many sub-fields in agriculture such as:

dairy (milk and cheese)
grains (wheat, corn, oats, etc.)
meat (beef, pork, lamb, poultry, eggs)
vegetables & greens
fruit orchards
vineyards
herbs
organic
fiber (wool, angora, etc.)
Do you want to specialize in one of the above, or do a little bit of everything? The trend in agriculture is towards commercialization and specialization. Generally, the larger the farm, the less diversified it is.

Find farms that you like. There might be some in your area, there might not. Ask around. Search the Web, and find out about county fairs and visit them. It's there that you'll find serious farmers. Talk to them. Ask them what they do, how their farms have changed over time, what direction they think the field is going in, and if you could stop by their farm and visit some time. Farmers are generally friendly, humble, and welcoming people, though some are more guarded than others.

Dress the part. This may sound superficial, but if you walked into a law firm interview dressed in a pair of jeans and boots, it's the same as walking onto a farm wearing a pair of dockers and loafers. If you're just starting out in farming, you're probably going to be doing a lot of physical labor. Wear a clean t-shirt, jeans, and work boots. Invest in a good pair of work gloves because your hands will be sore and full of blisters in a very short time. If you have long hair, tie it back (consider a braid) so it doesn't get caught in anything.

Become an apprentice. Offer your services as a laborer. This is the most critical step in becoming a farmer—working in exchange for an opportunity to learn. Since you're just starting out, you'll be entering at the bottom of the totem pole (as is the case in most careers).

If you get any criticism during this guide don't worry about it, just let everyone know that you had your vitamins this morning and therefore there is no way you can lose. I've had my fair share of criticism before finally deciding to upload this guide.
Just some of the questions I recieved while playing Mundo were,

"Why the **** did you invite Kye?"
"Why is he stealing blue buff?"
"Who the hell took my shoes!?!?"
(It was me, I took his shoes)

No matter what happens, remember, you are Dr. Mundo, you can't lose even if you're never played him before. Just follow my guide and everything will make sense momentarily.

If that doesn't work then you should try heroine, I hear its great for problems like this.