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The AP Shen that could
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Seals - I go 5 Defense 4 Resilience but like all runes pick up whatever you feel good with.
Glyphs - magic res per level! no question you may not be picking up any MR until guardian angel so I find this to be the best for it.
gogo Doran's Shield for that early game then go boots. after boots you can either go Warmog/Thornmail/Scepter/Guardian angel depending on this team comp.
Warmog - Pick this up if you are just dominating them early game so you can just out tank there damage
thornmail - If you are getting harassed by early game AD (trynda/YI ex.) then this will be your 2nd main item in the build
Scepter - If you are feeling good about how you are playing but it seems like you need that little damage push then pick this up over other items! it gives a nice HP bonus and give your VP-Faint a boost.
Guardian Angel - This is for though's games where you get the mix of AD/AP carry's. This will work wonders in your favor combo'd with warmogs later in the game.