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And your runes aren´t choosen well. U don´t need manareg and maybe some speedrunes and as-runes for the Greater Marks of Desolation.
This way u would make BIG DMG without much ap or ad^^ Madred´s + Wit´s End + Sword of the Divine + your passive e-skill = big magic dmg ...even tanks fall easily ;)
That´s the way i play her it works much better that pure AD or AP. I hope i could help u^^