vayne pro guide, this is the best for ultimate damage and still survive a big gank with the frozen mallet. the masteries and runes i think is perfect couse i use it and is really fine with it. the items is perfect for an ultimate damage build and still can survive pretty easy with the damage health Frozen Mallet. flash and heal make you perfect for Q to an enemie do your spells then kill the enemie, use heal if need and get away. with the attack damage and health u can survive almost everything in lvl 18 with still the kills! and the skill option in order is the perfect early damage order. and you have a very high movement speed to flee or chase your enemy down. As i said she have a high hp amount thanks to frozen mallet that still gives slow and base damage