Vayne, My only love is a guide for you who wants help playing Vayne. Vayne is a ranged AD carry and a perfect Jungler and Laner.

Hope you will like the build!

Marks
Laning as Vayne i recommend 5 Greater Mark of Desolatin wich will grant you a decent armor penentration wich will be perfecet laning and jungeling, the 4 other runes is Greater Mark of Strength to boost your at the start. Why Greater Mark of Strength at the start? Well i like to secure a "FB" with some decent AD. Why Greater Mark of Desolatin wich will? Well with no armor penentration your ad will almost be usless so that's why i choosed 5 Greater Mark of Desolatin wich will give some decent armor penentration and it will make your Greater Mark of Strength twice as good.

Seal
Playing as vayne you will need some atk speed and that's why i recommend Greater Seal of Alacrity. Greater Seal of Alacrity grants you a decent amount of atk speed.

Glyph
Playing as vayne i recommend Greater Glyph of Warding so you won't be worthless agienst an AP carry. Why Greater Glyph of Warding? Greater Glyph of Warding is the strongest Magic resitence rune and perfect for laning agienst an Ap

Im not planning to write so much about the items on Vayne but the things im going to write is relly simple. The build is relly a relly simple AD carry with some HP and AD and life steal and armor penentration. The build is NOT advanced but relly good for an AD.

The masteries is simply evrything on the left side at Offence and Havoc. At Defence i recommend using the Magic resist and Armor resist. There's nothing more complicated as that!

Here's the big part, Mostly people uses Tumble as their primary spell but when i play as Vayne i max Silver bolts wich deals a huge amout dmg in the ad carry part, In early game it's amazing! it will secure your first blood so easly if you'll get the 3 hits. I recommend playing with a stunner or a binder! If you're using Tumble Basic atk before tumbeling! it will give you 1 free basic + the amout dmg of Tumble. Condemn is one of the most OP things with vayne, try to push time in to a wall dealing more dmg and stunning

I play with Ghost as vayne giving her the chance to flee and chase them, Thanks to your passive Ghost will be relly usefull. Ignite is a basic summoner spell dealing True dmg a perfect ending or just put it out for the AD and AP.