LoL Best Vayne Build Guides 2025
Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!
Season 7 Builds
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4 EPIC VAYNE BUILDS + ONE SHOT VAYNE GUIDE
4 EPIC VAYNE BUILDS + ONE SHOT VAYNE GUIDE
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INSTAKILL ADC 2 AUTOS
Season 7 Vayne from someone who main Jhin
Vayne | ADC | S7 | Doublelift | Challenger
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Vayne Jungle Hyper Carry S7
Vayne Jungle Hyper Carry S7
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Vayne TVT
Assassin Vayne Build (6.22) Pre-Season 7
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Vayne Season 7 (Best Carry)
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Vayne S7[New meta???]
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VAYNE IS MY MAIN
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[6.22] Vayne Top- or Bot Lane!
[6.22] Vayne Top- or Bot Lane!
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Vayne | The three-shotting legend
Season 6 Guides
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Vayne Late Game Hyper Carry
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Pew Pew Pachoom! 3 shotting your way to victory with Vayne!
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Legendary Mechanics (FRESH - Tutorial Video + New Montage)
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Vayne's Tears Of Malevolence S6.18 (Unique Guide) Two Builds
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The Ultimate Vayne Guide
Vayne - The Hyper Carry
Vayne- For People Who Are Stuck In Elo Hell
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6.17 Vayne Split Push Top
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