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LoL Best Vayne Build Guides 2025

Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!



Season 10 Builds
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne adc

Build by oOTrrixOo updated September 13, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

bot lane / top lane vayne

Build by adc of adc updated September 12, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

ARAM-ONLY

Build by VanCleef updated September 9, 2020
7.5
6
Votes
1
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

600k mastery points diamond Vayne guide of swag

Build by Jakobskii updated August 31, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

baddest ***** on tiktok

Build by Manny poo 69 updated August 28, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne the BEST build on TOP

Build by kkBono updated August 21, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

GOSU Vayne Build

Build by Nothing here updated August 19, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Best Vayne Top Builds/Runes Challenger

Build by Homerjsinpso updated July 30, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Guia Vayne Season 10, Adc Y Top

Build by CaptainYisus updated June 14, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne TOP CARRY

Build by Xenomaniac updated May 14, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

OG thunderlords / electrocute vayne is back!

Build by kialor updated May 10, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

My Vayne build

Build by miro2 updated May 7, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

S10 Vayne ADC

Build by ScrollLock updated April 28, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

S10 Vayne Solo

Build by ScrollLock updated April 28, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Garet gets one shot by Vayne

Build by MrJeepMcFishTank updated April 21, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne is a good as Udyr

Build by Pingu Fugindo updated April 27, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne

Build by Do0n40oy11 updated April 22, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne tak o

Build by Mashhu updated April 15, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne I Strong

Build by ScorpionWoman17 updated April 10, 2020
Rating Pending
LoL Champion Vayne Build Guide
LoL Champion Vayne Build Guide

Vayne Korean Build/Runes

Build by Choquemaque updated April 5, 2020
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