3-10-6 Quinn and Nautilus vs Jinx and Thresh

I've upgraded this matchup to hard as laning against her isn't easy and late game she can just pelt you with rockets and you can't do much about it. Also if she is savvy with the positioning of her traps she can lob them where you are going to land after you Vault off of her.

It also helps to have a Nautilus that actually knows how to support and doesn't cost you half your farm by autoattacking it at inappropriate times.

3-8-9 Quinn and Nami vs Kennen and Nidalee

This lane is one that relies on reflexes and will depend heavily on your Nami support.

Levels 1-2 are easy. After that it gets hard. You have to really be on your toes to dodge Nidalee spears as they will chunk you for a quarter of your health. Nami can offset the damage somewhat, but not all of it.

The real problems start at level 6. If Kennen gets a Mark of the Storm on you he is going to Lightning Rush in, which allows him to ignore unit collisoin, to get another Mark of the Storm on you then he'll active Slicing Maelstrom, which is highly likely to apply a third mark of the storm to you, damaging and stunning you then activate Electrical Surge to deal even more damage to you. If you don't die from that, Nidalee will pounce in and finish the job.

Your Nami can mitigate all this to some extent if she is quick and accurate with Aqua Prison and Tidal Wave, but that is usually asking a lot of a soloqueue Nami.