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Leona can engage though minions, and her chain CC will almost always result in your death as you have no tools to escape. Make sure to stay out of her range at all times.
Pyke
Getting caught by Pyke's CC and high damage will ensure the death of you, as you have no tools to escape. Make sure to use minions as cover, and rush boots to dodge his hook
Blitzcrank
Getting hit by Blitzcrank's hook will almost always result in your death, especially if the enemy adc has cc to follow up, for example Jinx and Caitlyn traps. Use minions as cover, and rush boots to dodge hooks.
Alistar
Alistar can be a big threat, as his CC engage can easily result in your death. Stay out of his range at all times to prevent him from engaging on you.
Bard
Bard's CC with Q and R can be deadly to Sona, though these spells can be dodged easily if you stay out of range and rush boots.
Braum
Braum's CC engage is a danger for Sona, but if you stay out of range this is not a problem. Also make sure to use your ultimate when Braum can not block it with his shield.
Annie
Annie's burst damage can be very deadly, but Sona heavily out-scales Annie. Make sure to stay out of her range, as her point-and-click combo will result in your death.
Janna
Janna's early poke is better than Sona's, though she has no self-sustain like Sona. Your late game is slightly better than Janna's, so you will win if you don't fall behind early.
Karma
Karma has a better laning phase with poke, but worse late game. Make sure to not be hit by too many of Karma's Qs, and scale to win.
Lulu
Sona and Lulu have the same scaling and laning phase power. Her Q is a skillshot you can dodge, so bait it out, and after that you can poke her with your Q that will always hit. if you win early game, you win late game.
Lux
Getting hit by Lux' high damage combo can result in your death, and her long range can make it very hard to get through laning phase. Rush boots to dodge her spells to get through the early game, and do your best to win with your late game scaling.
Morgana
Morgana's CC and high damage can easily result in your death. Be sure to use minions as cover to prevent her from hitting her Q. Also make sure to use your R after Morgana already used her Blackshield.
Nami
Nami's early game is stronger than Sona's, though Sona outscales Nami in the late game. Make sure to not take too much poke in lane, and not to get hit by her bubbles and ultimate, as this CC can result in your death.
Nautilus
Nautilus' chain CC engage is highly dangerous and deadly. Make sure to use minions as cover to not get hooked, and stay out of his point-and-click ultimate, which will most often than not ensure your death.
Rakan
Rakan is highly mobile and can easily catch you off guard. Make sure to stay out of his range and use your ultimate to cancel his.
Rell
Rell's chain CC is highly deadly and getting caught by her will almost always result in your death. Stay out of her range and rush boots to dodge/escape her W.
Pantheon
Pantheon can easily kill you if you are caught by his CC followed by high damage. Make sure to stay out of his range so he can not leap to you resulting in your death.
Senna
Senna has long range and high damage which can make laning very hard. Senna's scaling is also near equal to Sona's. Get through laning phase and do your best to win late game.
Seraphine
Seraphine's long range CC and damage can be very deadly and make it hard to get through laning phase. Rush boots to dodge her spells and win late game with your scaling.
Soraka
Soraka has better sustain in lane, though she has no cc or burst damage to be a threat to Sona. Soraka's late game is also weaker due to no utility.
Swain
Swain's CC and damage combo is highly dangerous, and his spells go through minions. Stay out of his range and rush boots to dodge his spells. Scale to win.
Tahm Kench
Tahm Kench's CC can be dangerous, but he has no way of catching up to Sona, especially if you rush boots.
Taric
Taric has no threatening abilities besides his E stun, though this ability is easily dodged, especially if you stay out of his range.
Thresh
Thresh' combo will most of the time result in your death, especially if the enemy adc has CC as well. Stay behind minions and rush boots to dodge hook.
Vel'Koz
Vel'Koz has high damage and annoying poke that can make laning phase hard. Use minions as cover and rush boots to dodge spells.
Yuumi
Yuumi has no damage or cc that is a threat to Sona, besides her ultimate. Sona's scaling is around the same s Yuumi's, so win lane to be able to win late game.
Zilean
Zilean can be annoying to lane against, as he spams his Q and getting hit by 2 will result in your being stunned and possibly die if the enemy adc follows up. Stay out of his range and poke when his abilities are on cooldown.
Zyra
Zyra's CC and high damage combo and long range poke through minions can be very deadly. Rush boots to dodge her spells.
Aphelios
Aphelios can combo his ultimate nicely with Sona's, and they scale well together into the late game.
Ashe
Ashe and Sona has good ultimate CC chain synergy, and scale together very well into the late game. Ashe benefits heavily from Sona's movement speed aura.
Caitlyn
Caitlyn can follow up with traps and burst damage when you ult, making it a nice combo. Also scales nicely in the mid-late game, though not as hard as a hyper-carry.
Ezreal
Ezreal is an early game champion and doesn't scale that well with Sona, but still has good combo potential with ultimates.
Jinx
Jinx can combo traps and her ultimate into Sona's ultimate, and synergizes extremely well with Sona's late game scaling as a hyper-carry.
Jhin
Jhin has high damage and goes well with Sona, but doesn't scale as hard into the late game as a hypercarry.
Kai'Sa
Kai'Sa is an excellent hypercarry that goes well with Sona and benefits from Sona's buffs, though Sona cannot follow up on Kai'Sa's ultimate.
Kalista
Kalista heavily relies on a tank engage support to shine, and Sona can not fill that role for her, making Kalista lackluster.
Kog'Maw
Kog'Maw goes very well with Sona as he benefits heavily from her peel and buffs. They both scale greatly into the lategame together, though the have no abilities to combo.
Lucian
Lucian is an early game champion with high mobility. Sona can't really follow up with his dashes and don't scale together into the late game.
Miss Fortune
Though Miss Fortune doesn't scale as well into the late game as a hyper-carry, her ultimate combo with Sona is one of the deadliest in the game.
Samira
Samira goes best with an engage support as she is a high mobility marksman, making it hard for Sona to follow up. Ultimates can combo nicely together though.
Senna
Senna and Sona have very strong late game scaling, but at the cost of a not so strong early game. Also lackluster ability combo synergy.
Sivir
Sona and Sivir have no real ability combo synergy, and their scaling into the late game together is mediocre.
Tristana
Tristana is an early game, mobile, engage-based ADC, making it hard for Sona to follow up. Also no ability combo, and mediocre scaling.
Twitch
Twitch and Sona scale very well together into the late game, and have a deadly combo with their ultimates.
Xayah
Xayah scales nicely into the late game though not as well as a hypercarry. Her abilities combo good with Sona's though.
Vayne
Vayne and Sona have no abilities to combo, but their amazing late game scaling make up for it.
Varus
Varus and Sona scale very well into the late game, and also have amazing combo with their ultimates and basic abilities.
Synergies
IdealStrongOkLowNone
Aphelios
Aphelios can combo his ultimate nicely with Sona's, and they scale well together into the late game.
Ashe
Ashe and Sona has good ultimate CC chain synergy, and scale together very well into the late game. Ashe benefits heavily from Sona's movement speed aura.
Caitlyn
Caitlyn can follow up with traps and burst damage when you ult, making it a nice combo. Also scales nicely in the mid-late game, though not as hard as a hyper-carry.
Ezreal
Ezreal is an early game champion and doesn't scale that well with Sona, but still has good combo potential with ultimates.
Jinx
Jinx can combo traps and her ultimate into Sona's ultimate, and synergizes extremely well with Sona's late game scaling as a hyper-carry.
Jhin
Jhin has high damage and goes well with Sona, but doesn't scale as hard into the late game as a hypercarry.
Kai'Sa
Kai'Sa is an excellent hypercarry that goes well with Sona and benefits from Sona's buffs, though Sona cannot follow up on Kai'Sa's ultimate.
Kalista
Kalista heavily relies on a tank engage support to shine, and Sona can not fill that role for her, making Kalista lackluster.
Kog'Maw
Kog'Maw goes very well with Sona as he benefits heavily from her peel and buffs. They both scale greatly into the lategame together, though the have no abilities to combo.
Lucian
Lucian is an early game champion with high mobility. Sona can't really follow up with his dashes and don't scale together into the late game.
Miss Fortune
Though Miss Fortune doesn't scale as well into the late game as a hyper-carry, her ultimate combo with Sona is one of the deadliest in the game.
Samira
Samira goes best with an engage support as she is a high mobility marksman, making it hard for Sona to follow up. Ultimates can combo nicely together though.
Senna
Senna and Sona have very strong late game scaling, but at the cost of a not so strong early game. Also lackluster ability combo synergy.
Sivir
Sona and Sivir have no real ability combo synergy, and their scaling into the late game together is mediocre.
Tristana
Tristana is an early game, mobile, engage-based ADC, making it hard for Sona to follow up. Also no ability combo, and mediocre scaling.
Twitch
Twitch and Sona scale very well together into the late game, and have a deadly combo with their ultimates.
Xayah
Xayah scales nicely into the late game though not as well as a hypercarry. Her abilities combo good with Sona's though.
Vayne
Vayne and Sona have no abilities to combo, but their amazing late game scaling make up for it.
Varus
Varus and Sona scale very well into the late game, and also have amazing combo with their ultimates and basic abilities.
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