Incase you missed any notes along the Guide:

Summoner Spells

.Flash and Ignite- General go to due to karma's agressive laning phase.
.Flash and Exast- Good if you want to shutdown a specific carry.

Starting Items

.ALWAYS take Spelthieves Edge on Karma, there is not a single lane in the game i can think about where relic shield would bennifit you over the former option. You are a lane bully, if you going to sit back and "afk the lane" dont play karma, try someone like sona, soraka, lulu or anyone else that scales well into the late game.

Mythic Item Options

Enchanter Items- Shurelya's/Moonstone/Imperial Mandate.

Both items are viable depending on the situation you find yourself in. Out of the 2 Moonstone is your go to item that you can build pretty much every game, if you arent sure what to itemize. Moonstone is a great option if you are looking to play long teamfights and have good frontline on your team, your buffed shields and heals from moonstone will be huge! speacially given the new durability changes, fights will last longer making it much easier to get multiple Moonstone heal procs. On this patch shurelyas is not karmas optimal item anymore, but its still very viable, it provides great utility with the speed boost on the active and the item passive on your shields, helping your team engage, or disengage in fights. Overall its up to personal preference and your and the enemy's team comps. Imperial mandate, just dont do it :)

AP Mythics- Ludens and Lyandris

For the most part i dont advise buying these items over Shurelya's or Moonstone. In very specific cases when you are very ahead they can be great to boost your damage and allow you to have more impact on games. Out of these Luden's Tempest is the best option in my experience for raw burst. Liandry's Anguish can be bought in games where the enemy has lots of hp stacking champions and you dont have a lot of ap damage on your team.

Booties!

You should buy ionion boots of lucidity every single game! Unless the enemy team has 3 or more high cc champions, in which case you should opt for Mercury's threads, or the enemy team picked full ad or a team that consists of a lot of ad assasins (qiyana, talon, zed, kha'zix) you can buy plated steelcaps instead.

Reccomended Legendary Items

By default karma is a champion with average ap ratios, she scales much better with ability haste. All the items listed above are great purchases on karma, Chemtech Dutrifier is great in most games, since most teams will have some sort of healing, Sedemption and Staff of Flowing Water are amazing items on karma that can be built pretty much in any situation. Ardent Censor is great if your team has 2 or more champions that synergise well with atack speed or on hit, such as hypercarry adcs (kog maw, vayne, jinx). Michaels Crucible can be bought in games when you have to cleanse a certain "death cc", helping keep your carries alive. Finally VIgilant Wardstone is a very underated item that can be purchased as a 3rd or 4th item most games since they usually dont go past 25/30 minutes.

Situational Items- Cosmic Drive/Zhonyas Hourglass/Horizon Focus/Void Staff

Great little situational items that are taken mostly in ap builds. Cosmic drive allows you to somewhat kite and gives an insane ammount of ability haste, Zhonyas is great against hard dive comps, assasins or heavy burst that is focused on you, Horizon Focus is a pretty cool item if you are very ahead, it makes your mantra+q poke chunk health bars and gives you a decent ammount of ability haste too! Finally and the option i most rarely take, if you are going into extremely tanky teams and your comp lacks ap, you can build a void staff too help take down those heavy frontliners.

Skill Order

You want to almost always be maxing your q anility first, then your e ability, and finally your w ability, obviously upping your mantra(r ability) whenever you can!
If you are winning lane very hard and want to opt into an Ap mythic maxing q into e is also a viable option.

Runes- Summon Aery/Arcane Commet/Guardian

Karma can use all 3 of these rune pages very well. Aery build is currently the best, you should always take it if you plan on building Moonstone as your mythic item, and most other games too. Arcane Commet is an option for very agressive laners that have some experience on karma and know how to exploit her early game very well. Honestly i dont like guardian at all, its once more a sit and afk kind of rune, you are not soraka, yuumi etc play agressive and take one of the other 2 options. The only situations i would advise guardian is if you are new to karma and never played her, or if you are not confortable into engage champions such as Leona, Rell, Nautillus, Blitz you get the point. But honestly learn after you learn karma, you should pretty much always take aery!

About me

Hello there! Im a EUW Karma Main and this is my Support Karma Guide. I have been playing her since i started playing the game in end of season 9, and managed to reach platinum in my first season. So far in season 12 i have managed to climb to diamond 3 for the first time! I hope you enjoyed this guide and find it helpfull in any way, im happy to answer any and all questions, on this page or you can also add me in game @Keisari Karma.