PROS + Long range + High damage + Good roams + Stealthy + Strong lategame Twitch has very high damage lategame, and his Ambush provides him with incredible roaming and cheese potential in the early game. His Spray and Pray is an incredible attack damage steriod that makes him a longranged powerhouse for its duration.

CONS - Squishy - No crowd control - Low utility - Difficult to play - Weak Early Twitch is one of the only adcs to have no major crowd control in his kit. He has absolutely no tools to keep himself alive, making him an incredibly complex champion to learn and play. He relies on creative use of Ambush to keep him in line with other adcs, especially in early game.

PASSIVE ABILITY

Deadly Venom ✦ Twitch's basic attacks apply poison, doing true damage over 6 seconds, stacking up to 6 times. The damage from this ability is negligable.

Q

Ambush ✦ Twitch enters camouflage and gains movespeed for 10-14 seconds. He is revealed whenever he walks within a certain radius of a champion or control ward. His first auto or ability cast will end the camouflage, and give him an attack speed steriod for 5 seconds. This ability is used to get the jump on enemies, and give Twitch a huge burst of damage.

W

Venom Cask ✦ Twitch throws down a toxic cloud in an AOE that lasts for 3 seconds. Enemies in the radius are slowed and gain a stack of deadly venom each second they are in the radius. This is Twitch's only crowd control tool. It can also be used to clear wave in combination with Contaminate.

E

Contaminate ✦ Twitch deals damage to all nearby enemies based on how many Deadly Venom stacks they have. This ability is best used for massive burst damage at the end of a fight.

R

Spray and Pray ✦ for the next 6 seconds, Twitch gains 300 attack range, a large amount of AD, and his attacks become piercing bolts. Best used at the start of a teamfight. For the duration, Twitch becomes an incredibly scary champion who can dish out enough damage to wipe an entire team.

SUMMONER SPELLS - FLASH: Twitch takes Flash every single game. Twitch has no mobility built into his kit, and Flash offers him an incredible amount of utility. It can be used to follow for kills, engage on fights, escape certain doom. Twitch usually wants to hold on to Flash to use it defensively. GHOST: Ghost is my favorite option for a second summoner on Twitch. It offers him a great amount of utility, especially for chasing low health enemies and escaping bad situations. There is nothing in the entire game more terrifying than a Twitch coming out of Ambush with Spray and Pray and Ghost. HEAL: I recommend Heal for new players who are less confident or in very strong early lanes. Exhaust:I usually do not reccommend Exhaust, but occasionally when paired with an enchanter into a strong early lane it's better for the enchanter to have Heal and you to have Exhaust. It's best used to shut down high damage champions. Cleanse:I don't find myself taking Cleanse very much, because Twitch is uniquely able to avoid bad situations with cc because of Ambush. It's still sometimes worth taking into really heavy cc teams.

Lethal Tempo

Lethal Tempo is Twitch's best main rune by far. It gives him bonus damage in extended fights, and extra range and safety in lategame. It's worth mentioning, there are a couple of Twitch players who swear by Press the Attack for its burst damage and synergy with Contaminate. I still much prefer Lethal Tempo.

Triumph is the best option of the first set. It helps Twitch snowball in bloody games and keeps him alive during lategame teamfights.

For the Legend runes, I take Legend: Alacrity for the incredible attack speed scaling it provides lategame.

For the third set you can run either Coup de Grace or Cut Down. Coup de Grace is better into squishy teams, and Cut Down is better into tankier teams.

Inspiration

VS

Domination

Inspirationis a standard secondary pick, and I go it most games. I take Biscuit Delivery for lane sustain, and Magical Footwear for the gold value and movement it provides. Overall, just a good standard safe pick that you usually can't go wrong with.

Domination secondary is a more niche pick, and I usually only take it in games where I'm partnered witha strong engage support into a weak early game. I take Eyeball Collection and Treasure Hunter to help snowball out of control.

Berserker's Greaves Build first every game. The amount of value the attack and movement speed Berserker's Greaves provides is unmatched. Especially for Twitch, Berserker's Greaves helps Twitch roam around the map and look for kills with Ambush

Blade of the Ruined King Blade of the Ruined King is very powerful because of its abilities. The movement speed on third hit, lifesteal, and percent current health damage are all incredibly valuable and useful tools. It perfectly compliments Twitch's hybrid adc assassin playstyle.

Guinsoo's rageblade Guinsoo's Rageblade is just a huge damage statbuff. It doesn't do anything else, and it doesn't really need to. It plays into the rest of Twitch's kit to make his lategame even scarier.

Runaan's Hurricane Runaan's Hurricane comboes into the rest of Twitch's high damage kit, especially Contaminate and Spray and Pray to transform him into a terrifying AOE murder powerhouse. Once you build this item, you start to look for more teamfights.

Bloodthirster Bloodthirster provides sustain in extended fights for Twitch. It's best picked in games where you take anavoidable poke/burn damage. Counterintuitively, I would not reccomend this into teams with high burst damage, like Zed or Ahri because they can usually kill you before the healing can really take into effect.

Guardian Angel Guardian Angel is best taken when you are incredibly ahead and a signifigant portion of your teams damage, and/or when you find yourself getting picked off at the start of fights.

Lord Dominik's Regards Lord Dominik's Regards is an anti-tank statstick. It is built into tanky teams you'd otherwise have trouble shredding.

Mercurial Scimitar Mercurial Scimitar is mostly built into Malzahar and Mordekaiser. It's active item allows you to cleanse both of their ultimates, which would otherwise mean certain doom. Other than that, there are a couple situations where you get focused down by a very heavy cc team.

Mortal Reminder Mortal Reminder is the adc's answer to an antiheal item. Generally you get less value out of it than you do other items, and you're better off having other teammates build antiheal, but it's solo queue and cooperative teammates are a myth, and it's better than you have antiheal than nobody having antiheal.

Maw of Malmortius Maw of Malmortius is the strongest anti-mage item in the game. It's very good when you find yourself being bursted down by magic damage threats. However, I don't usually reccomend building it because Twitch is very good at avoiding being bursted down with creative use of Ambush.

Kraken Slayer Kraken Slayer is a good general damage item, but I find myself taking it very rarely over Lord Dominik's Regards when I need more damage into tanks, and defensive items when I need to not die.

AP Twitch

★ There is an AP variant of Twitch with Nashor's Tooth and Hail of Blades. Essentially you're trading off dps for burst damage on Contaminate This means a much more powerful early game, at the cost of a much weaker lategame. Your gameplay loop becomes much more typical to that of an AP assassin. I generally think that the AD build is a lot stonger, but the AP build certainly isn't bad. AP can also be run support and midlane. If you're curious about the AP build, I reccomend this lovely guide by Exolol

For when you don't know where to ward in laning phase. You can also ward bot bushes, but that's very situational and I'd generally let the support do that.

Some quick tips on how to ward efficiantly!
Generally Stealth Ward is best used outside of bushes, in choke points the enemy is likely to be forced to walk past. For example, if you're pushed up you'll want to ward somewhere in bot river in case jungler is roaming down.
Control wards are best used in places where the enemy is likely to have warded. Tribush is the most common example. It's very important for at least one person to have control warded an objective for a teamfight, to deny vision.

Twitch's Ambush is one of the most complex tools in his kit. In a lot of ways, you want to be playing him a little bit like Evelynn. You should be looking to use it to generate advantages wherever possible. Set up the suprise 1v2, roam and get some kills midlane, even use it in botlane to bait an engage on your support. You want to use this ability as much as possible. It is Twitch's bread and butter.

Early game as Twitch you have two goals. Gain as much cs as possible to help snowball you into mid and lategame, and use Ambush to try and look for cheesy roams and fights. If you manage to get ahead as Twitch, you become a snowball assassin, much like Talon. It's very important that you buy control wards whenever possible and contest as much vision as you possible can, especially to help jungler if they go for an early dragon.

Mid game as Twitch you want to focus on generating personal gold wherever possible, as well as dishing out as much damage in teamfights as you can. Usually at this part of the game you want to swap with midlane and buy Farsight Alteration. As much as you're looking for personal gold and value, at this point in the game you're relatively important. You want to be looking to help with objective fights, roaming around the map and lending a helping hand wherever possible. It's generally pretty important to stay close to your support, even at this point in the game, because basically everything can murder you if you get caught out.

Finally! You've reached lategame! Now your objective is to dish out as much damage as humanly possible with Ambush, Ghost, and Spray and Pray. At this point of the game you are the carry, and you need to act like it. Generally you want to wait to join fights from Ambush until after the enemy team has used important crowd control abilities. You're very useful on the back ends of fights, after everyone else has their abilities on cooldown. It's also worth looking for weirder angles with Ambush so you can avoid getting hit by AOE abilities.

You've reached the end of my little guide!
Huge shoutouts to:
Breadedbreadcrum for looking over my guide helping me figure out the terror that is BBcode. Check out her Ivern guide.
Jraff, for teaching me botlane concepts and helping with matchups (also apparantly he has a leaguepedia page? Rad.)Check out his Twitch.
Jhoihoi's Making a Guide Guide, for most of the graphics.
I'd like to shoutout Aerenax, for letting me yoink their code for matchups and giving me the idea to color hyperlinks for visual cohesion. Check out their Alistar guide.
Thank you to Faithk for his invaluable help. Check out his esports startup, Ekuso, which focuses on providing an esports experience to middle and high schoolers.
And lastly, the fine folks on the Mobafire discord server, this would not be possible without ya'll.