Flash - You can also take ghost, but for this runes and build i prefer Flash

Smite - Always Take Smite if you going to play jungle !

Ghost - If You choose PREDATOR for your keystone in domination runes, you always want to take this spell.

Take Domination as Primary Path:


ELECTROCUTE - This keystone is good cuz rengar can spam his abilities and its easy for proc.

SUDDEN IMPACT - This is CORE Tier 3 Keystone cuz you have your leap(R- Thrill Of The Hunt/P - Unseen Predator)

EYEBAL COLLECTION - CORE Tier 2 Keystone cuz you have your Passive Bonetooh Necklase, and if you take this keystone, your bonetooh necklase have "upgrade" :D

RAVENOUS HUNTER - More Sustain More Prizes :D

For Your Secondary Path you can choose Precision, cuz its good for 1v1 fightnings.

TRIUMPH - This keystone is good cuz if Rengar ganks, for example, bot lane, he will miss a lot of HP, but if you have this keystone, you will refund 15% of health missing + grand 25 additional gold.

LAST STAND - This keystone is good for 1v1 fightnings, and you can take it if you strongly focusing on ganks in early game.

Pros

-Can Oneshot
-Hard to kill 1v1
-Tons of damage.
-Good Jungle Clear

Cons

-Non'Tank
-Weak to CC[Stuns,Snares,Silences...]
-Useless in Teamfight Without Thrill Of The Hunt[R] or brushes