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Introduction
For Runes, I take:
Flat AP magic pen (this is because you want to shred your opponent's MR and completely dominate)
Flat AD glyphs (again, you want to trigger her passive at level 1)
MR Per Level Seals (since you are in the mid lane, most of the other's in the mid will be AP and magic damage based. These will help you stay in the lane longer and win more 1v1s, as well as help you late game)
AP Per Level Quints (Akali should be played more towards AP, so these will ehlp you greatly)
Flat AP magic pen (this is because you want to shred your opponent's MR and completely dominate)
Flat AD glyphs (again, you want to trigger her passive at level 1)
MR Per Level Seals (since you are in the mid lane, most of the other's in the mid will be AP and magic damage based. These will help you stay in the lane longer and win more 1v1s, as well as help you late game)
AP Per Level Quints (Akali should be played more towards AP, so these will ehlp you greatly)
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