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Belly Full of Jelly
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all the other runes are best for early game lane dominance and fast farming gragas and thats exactly the thing you want at the start.
If u want to get more dominance at the start then go with a 21/0/9 picking up all ap u can get and the cooldown reductions. Just don't forget to pick Runic Affinity to keep that blue buff on your self for that bit longer.
When you first come back you should have farmed up a good amount of gold (if u struggle farming see the farming chapter). What you should aim to get is two Dorian rings and if u have farmed really well you might be able to get your sorcerer's shoes but if u haven't farmed that well get another doran's ring so u have three or if you have a hard opponent then get hp pots assuming you have used your other once.
Second visit back get your shoes and Blazing Wand or get Niddlessly Large Rod if u have three Doran's and like 1400 gold then just sell one ring and get that Rod it would mean that you will dominate your lane like a Boss.
Then you should gank with your ult and body slam it shouldn't be hard but ask your team mates to engage in a fight not just stand and wait for you to do everything by yourself.
By your next visit to the town you should have plenty of gold +kill and an assist so i prefer to get Deathcap perfect item for gragas that ap is so good you would clear out a wave of minions with just a barell roll and with some help from a body slam all exp and gold is yours. I also like to get a mejai's soulstealer if i get a lot of assists and kills. That does it for me actually then i see how the team fights are going if they are in my teams favor then i get a lich Bane if not go with Rod of Ages for more HP.