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Get to Gold with Annie
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Why is Annie great for carrying?: Because she is fantastic at making the plays happen and deciding when you fight. Even if your team is behind you can still kill the other teams carries in one combo.
Quintessence: There is really no discussion here, the flat ap is really great for the early and i value it over the magic pen quints.
Marks: I use magic pen marks to help me burn through tanks.
Seals: Scaling health seals are the most common seal mid lane because you mostly face magic damage midlaners so armour is basically useless. You can go armor if you don't have the IP to spend on scaling health or if you face a champion such as zed.
Glyphs: Why not use CDR glyphs? Simply because my items give me the CDR i need to hit 40%.
Magic resist helps you a lot against other mages in lane and later in the game.