This is my second Malzahar Guide. Enjoy it :)

Essenz - 3x Ability Power
Marks - 9x Penetration
Glyhes - 9x Magic Resist
Seals - 6x Scaling Armor 3x Scaling Health

Utility with Expanded Mind for more Dmg at Archangel´s Staff and Artificer for Archangel´s Staff, Zhonya´s Hourglass, and if you pick Deathfire Grap, Active Reduktion

Start with Crystal and 2 Health Potion´s for Mana. Then by the first Stop, buy Catalyst the Protector or if you have not enough money buy Ruby Cristal. Then follow the Item List

1st Idea: First Spell is Call of the Void then Malefic Visions, Ignite, Null Zone and Nether Grasp.
2nd Idea: First Spell is Call of the Void then Malefic Visions, Null Zone, Nether Grasp and Ignite

Look at Abilities.

At the early game you do "no" Dmg. But if you have Rod of Ages the battles can begin.

At the begin attack the minions and cast Malefic Visions to kill them. If you have Rabadon´s Deathcap cast Call of the Void for one hits.

At Jungling cast Call of the Void, Null Zone and Malefic Visions. Thats easy

Important is Call of the Void and Null Zone to Silence the Enemies and do Damage. A little support is Nether Grasp to stun the enemies ^^.

Very important is Catalyst the Protector´s skill to earn Mana and Health.

Not jet

No idea