Welcome ladies and gentleman,
to my genius guide for singed.

The reason why this is so smart is because of his passive.
you will get an insane amount of hp while buying mana.

I am still working on this guide so please, leave tips in the comments.

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Singed descended from a long line of Zaun's revered chemists. Even in his youth, his talent for concocting potions far outstripped that of his peers, and he quickly distinguished himself from his less extraordinary chemist compatriots. It came as no surprise to anyone when he was selected for apprenticeship by the infamous Warwick, master apothecary on a lucrative retainer with the Noxian military during their campaign against Ionia. Within Warwick's laboratories, Singed toiled without end, rapidly absorbing every detail of his predecessor's deadly craft. Singed had little concern for the death and destruction that was the fruit of his labors. By the time the curse of lycanthropy descended to claim his master, Singed was poised and eager to make the transition from workhorse to innovator; he was ready to share his genius by bringing a new brand of suffering to the Ionian front. His zeal for progress was unquenchable, and when suitable test subjects proved to be in short supply, the eager chemist was often thought to turn his volatile mixtures on his own flesh.

When the uneasy peace created by the League of Legends settled on the world, Singed journeyed to the one place where he was still able to showcase his beloved craft: the Institute of War. By this time he was barely even a man, his body both ruined and sustained by his ingenious craft. A thousand burns - accidents of shadow and flame - mar his ravaged form, and exposure to such harsh conditions has deadened his nerves, hardened his body, and strengthened his physique, transforming him into a veritable juggernaut. This, combined with a formidable arsenal of deadly concoctions, makes Singed a force to be reckoned with on the Fields of Justice.

"My deadliest dose shall bear my patron's name!" - Singed, having just christened the Insanity Potion

MARKS: for marks I have chosen magic pen, are there even other marks in this game?

SEALS: Seals was just as easy, Mana! because it makes you an early game tank.

GLYPHS: Have you been reading? then you know the answer

QUINTESSENCES: I prefer getting catalyst before boots and the overall movement makes me faster than

Mana crystal is very usefull since it leaves you money for potions and grants mana and hp.
other options are dorans ring or boots of speed.
Catalyst is a really usefull early game item in lane because you get hp when you lvl up, making you more sustainable.
Tear is situational, i like the mana regen early.
you could get catalyst - boots of speed - rod of ages - mercury treads
If you are vs an ap top, get banshee before glacial shroud.
If you are vs an ad top, get glacial shroud first.
Rylai's sceptre allows you do keep outrunning your enemies without boots of swiftness.

Empowered Bulwark
Increases Singed's health by .25 for each mana point he has.

Poison Trail
Toggle: Singed lays a poisonous trail which lasts for 3.25 seconds and deals 22 / 34 / 46 / 58 / 70 (+30% of ability power) magic damage per second to enemies for 3 seconds.

Mega Adhesive
Singed throws a vial of mega adhesive on the ground causing all enemies who touch it to be slowed by 35 / 45 / 55 / 65 / 75% for as long as they are in the adhesive and for 1 second once they are out of it.

Fling
Singed flings an enemy over his shoulder (500 units), dealing 100 / 150 / 200 / 250 / 300 (+100% of ability power) magic damage.

Insanity Potion
Singed drinks a potent brew of chemicals, granting him 10 / 15 / 20% crowd control reduction and 35 / 50 / 65 ability power, armor, magic resistance, movement speed, health regeneration per 5, and mana regeneration per 5 for 25 seconds.

On singed anything workes.

Flash - He doesn't have any reliable escape tools

Heal - Just heal, makes towerdiving more easily

Clarity - Not my favourite but it could be helpfull if you have mana problems

Ghost - good for chasing opponents you want to throw

Teleport - easy if you dont want to walk back, or suprise gank

Exhaust - good vs attackspeed champs like teemo

Ignite - to get the kill

I have no idea if this build actually works, ill try to uplode some results soon