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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.10
9.2
581
Votes
35
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

πŸ’€[NEW SEASON 15] CASSIOPEIA - The POISON Queen of Midlane ☠ πŸ’€

Guide by RezoneVerified updated May 16, 2025
  • In-depth
9.2
2685
Votes
168
LoL Champion Heimerdinger Build Guide
LoL Champion Heimerdinger Build Guide

πŸ”§[ 25.10 MASTER TIER 9.7 MILLION MASTERY HEIMERDINGER πŸ”§ SEASON 15 ]

Guide by RezoneVerified updated May 16, 2025
  • In-depth
9.2
206
Votes
22
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.10] PrestigeGalaxy's 5M+ Mastery Guide to Katarina! πŸ—‘οΈ

Guide by PrestigeGalaxy updated May 14, 2025
  • In-depth
8.9
15
Votes
1
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

[15.2] βœ”οΈ In-Depth Qiyana guide - Master the Empress of the Elements

Guide by gimmelovej updated May 14, 2025
  • In-depth
8.9
37
Votes
5
LoL Champion Ziggs Build Guide
LoL Champion Ziggs Build Guide

A Comprehensive Ziggs Primer

Guide by Laimaudeja updated May 16, 2025
  • In-depth
8.9
477
Votes
38
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

⚑ [SEASON 15 UPDATED!! ] Master Tier Midlane Orianna! THE BALLS HURT ⚑

Guide by RezoneVerified updated May 16, 2025
  • In-depth
8.9
275
Votes
24
LoL Champion Cho'Gath Build Guide
LoL Champion Cho'Gath Build Guide

[Season 14] Sakuritou Challenger Rank 1 Cho'Gath World Guide

Guide by Sakuritou updated May 16, 2025
  • In-depth
8.9
646
Votes
51
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

πŸ‘‰ 🧊[ NEW SEASON 15 ] - Master's Guide to Midlane ANIVIA! S TIER PICK! 🧊 πŸ‘ˆ

Guide by RezoneVerified updated May 16, 2025
  • In-depth
8.9
70
Votes
9
LoL Champion Nasus Build Guide
LoL Champion Nasus Build Guide

[25.10] Nasus Mid OTP - Simplest In-Depth Guide S2025

Guide by SurferKiller updated May 15, 2025
  • In-depth
8.7
23
Votes
4
LoL Champion Syndra Build Guide
LoL Champion Syndra Build Guide

15.10 My Potential is Limitless

Guide by Demonsedge90 updated May 15, 2025
  • In-depth
8.6
12
Votes
1
LoL Champion Aurelion Sol Build Guide
LoL Champion Aurelion Sol Build Guide

[Patch 15.10] Master OTP Season 15 Aurelion Sol Guide

Guide by Event Horizon updated May 17, 2025
  • In-depth
8.6
309
Votes
25
LoL Champion Hwei Build Guide
LoL Champion Hwei Build Guide

[Patch 25.10] Hwei Season 15 Guide By Azzapp [Mid/APC/Sup]

Guide by Azzapp updated May 17, 2025
8.3
7
Votes
0
LoL Champion Xerath Build Guide
LoL Champion Xerath Build Guide

Rank 1 EUW/EUNE XERATH Dominating Midlane Guide

Guide by Hofibauer updated May 18, 2025
8.3
7
Votes
0
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.10] Victorious Twisted Fate Guide for Season 15 | Jammed

Guide by Jammed updated May 17, 2025
  • In-depth
8.3
16
Votes
3
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

[Patch 25.10] S15 CHALLENGER AURORA GUIDE (will update as I climb)

Guide by Tokiyami updated May 14, 2025
  • In-depth
8.3
10
Votes
1
LoL Champion Malphite Build Guide
LoL Champion Malphite Build Guide

Glass Cannon AP Malphite Mid

Guide by Marky 2 Butts updated May 14, 2025
8
25
Votes
7
LoL Champion Cho'Gath Build Guide
LoL Champion Cho'Gath Build Guide

[Season 14] Sakuritou Mathematically Correct Cho'Gath

Guide by Sakuritou updated May 16, 2025
8
523
Votes
68
LoL Champion Swain Build Guide
LoL Champion Swain Build Guide

[ Patch 25.10 NEW SEASON 15 UPDATED!! ] - SWAIN is the GOD OF MIDLANE PAIN! - 🀯

Guide by RezoneVerified updated May 16, 2025
  • In-depth
8
120
Votes
21
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

[ AURORA MIDLANE GUIDE SEASON 15 - 25.10 🐰[AURORA IS THE MOST ANNOYING MIDLANER 2025]

Guide by RezoneVerified updated May 16, 2025
  • In-depth
7.7
11
Votes
3
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Vlad 15.10+ Item Guide

Guide by KormitLeFrag updated May 17, 2025

League of Legends Champions:

Teamfight Tactics Guide