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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 3 Guides // Patch 25.18
8.3
243
Votes
22
LoL Champion Aurelion Sol Build Guide
LoL Champion Aurelion Sol Build Guide

[Patch 25.18] SEASON 15 Aurelion Sol Guide by Azzapp

Guide by Azzapp updated September 13, 2025
8.3
650
Votes
54
LoL Champion Anivia Build Guide
LoL Champion Anivia Build Guide

👉 🧊[ NEW SEASON 15 ] - Master's Guide to Midlane ANIVIA! S TIER PICK! 🧊 👈

Guide by RezoneVerified updated September 10, 2025
  • In-depth
8.2
9
Votes
1
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

I'm not arrogant, I'm right Qiyana|25.18| GUIDE MID+JNG

Guide by Deylan updated September 13, 2025
7.7
25
Votes
9
LoL Champion Cho'Gath Build Guide
LoL Champion Cho'Gath Build Guide

[Season 14] Sakuritou Mathematically Correct Cho'Gath

Guide by Sakuritou updated September 10, 2025
  • In-depth
7.3
17
Votes
9
LoL Champion Yasuo Build Guide
LoL Champion Yasuo Build Guide

[Season 14] Sakuritou Challenger Yasuo Guide

Guide by Sakuritou updated September 10, 2025
Rating Pending
LoL Champion Ahri Build Guide
LoL Champion Ahri Build Guide

Textwall Tryhard Ahri guide by Streetmagiks

Guide by streetmagiks updated September 13, 2025
  • In-depth
6.7
17
Votes
10
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

[Season 14] Sakuritou Challenger Yone Guide

Guide by Sakuritou updated September 10, 2025
Rating Pending
LoL Champion Quinn Build Guide
LoL Champion Quinn Build Guide

Winged Victory: Dominate Mid with Quinn 🦅

Guide by Quinfrey updated September 12, 2025
  • In-depth
6.3
6
Votes
5
LoL Champion Mel Build Guide
LoL Champion Mel Build Guide

[S15] Arcane AP Mid/Bot ♡

Guide by millysenpai updated September 11, 2025
  • In-depth
5.2
12
Votes
14
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[Season 14] Sakuritou Challenger Katarina Guide

Guide by Sakuritou updated September 10, 2025
2025, Season 3 Guides // Other Patches
10
240
Votes
15
LoL Champion Galio Build Guide
LoL Champion Galio Build Guide

[25.17] Hexeria's detailed Masters Guide to Galio

Guide by Hexeria updated September 8, 2025
  • In-depth
10
602
Votes
20
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Elite500, UNDISPUTED #1 VLAD PATCH 25.17

Guide by Elite500 updated September 8, 2025
  • In-depth
9.8
832
Votes
54
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.17] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated August 28, 2025
  • In-depth
9.7
180
Votes
15
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[15.17] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.5
591
Votes
36
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 16] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated September 8, 2025
  • In-depth
9.5
1989
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.17] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated September 2, 2025
9.5
492
Votes
36
LoL Champion Lissandra Build Guide
LoL Champion Lissandra Build Guide

🍦 [ 25.17 - SEASON 15 - The MIDLANE ICE QUEEN OF DEATH! 🍦

Guide by RezoneVerified updated August 31, 2025
  • In-depth
9.5
987
Votes
77
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

[15.17] Rank 1 Kassadin Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.5
355
Votes
30
LoL Champion Malzahar Build Guide
LoL Champion Malzahar Build Guide

[15.17] Rank 1 Malzahar Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.2
2695
Votes
169
LoL Champion Heimerdinger Build Guide
LoL Champion Heimerdinger Build Guide

🔧[ 25.17 MASTER TIER 10 MILLION MASTERY HEIMERDINGER 🔧 SEASON 16 ]

Guide by RezoneVerified updated September 8, 2025
  • In-depth
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League of Legends Champions:

AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYunaraYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide