1.SKILLS
Deadly Venom - Twitch's attacks infect the target with Deadly Venom, which deals damage each second, stacks up to 6 times, and lasts up to 6 seconds.
Ambush - Twitch hides in the shadows, waiting for a nearby enemy. If he attacks, he will gain bonus attack speed.
After 1.25 seconds, Twitch becomes stealthed for 10/20/30/40/50 seconds. If Twitch attacks a unit while Stealthed, he gains 30/40/50/60/70% attack speed for up to 10 seconds, depending on how long he was stealthed before attacking.

Cost
60/60/60/60/60 Mana
Range
20
Debilitating Poison - Infects all nearby champions with Debilitating Poison, slowing their movement speed.
Slows nearby enemy champions' move speed by 30%, plus 6% per Deadly Venom they have.
2/2.6/3.2/3.8/4.4 second duration.

Cost
80/80/80/80/80 Mana
Range
1200
Expunge - All nearby enemies secrete Twitch's toxic venoms from their bodies, dealing damage for each stack.
Deals 30/60/90/120/150 (+1) magic damage to each nearby poisoned enemy, plus 20/30/40/50/60 additional damage per stack of Deadly Venom applied to them.

Cost
90/90/90/90/90 Mana
Range
1200
Spray and Pray - Twitch closes his eyes and fires his crossbow, spraying powerful piercing arrows ahead of him.
Twitch's attacks become long range, passing through units, and he gains 15/25/35 Attack Damage.

Lasts 12 seconds or 5/6/7 attacks.

Cost
150/150/150 Mana
Range
1200

TWITCH STORY
The city-state of Zaun is a twisted realm of science, mercantilism, and magic run amok. While the young science of techmaturgy does much to advance civilization, its research and use in Zaun pushes the boundaries of morality on a daily basis. Zaun, choked with pollution from the countless factories and laboratories that spew waste into the environment, suffers greatly. As polluted as Zaun is above-ground, its subterranean levels are far worse. All of Zaun's runoff waste pooled together in its sewers, mixing into a toxic and mysterious concoction. A single plague rat rose from this alchemical nightmare - Twitch. Unlike his lesser evolved cousins, Twitch became as sentient as anyone else... provided they were as insane as he. A seeming byproduct of the evolutionary brew that spawned him was maniacal insanity, albeit in a functional form.

Twitch came to the League of Legends to represent himself ''as the only one of his kind'' on the Fields of Justice. Since then, he has found a generous benefactor in the city that gave him his evolutionary sentience - Zaun. Twitch is one of Zaun's premier champions in the League, and as such he fights for Zaun when political disputes between Valoran's city-states arise. Twitch has publically stated that his goal is to gain enough influence and materiel from his work in the League to try to recreate the process by which he gained his sentience. While many challenges lie ahead in his quest - one of the largest being his own insanity - were he to succeed, it would mean a bold and brazen step forward in the evolution of all of Runeterra. Zaun has pledged its support for Twitch in his quest, though it remains to be seen what Zaun's ulterior motives are in the matter.

''The existence of Twitch proves that anything is possible on Runeterra.''
-- Heimerdinger


2.ITEMS
Boots,There are two ways to wear. If you play Mostly on the line wear Berserkerer GreaversBut if you are very often Ganking Buy Boots of MobilityThan Black cleaverIts best item for twitch it gives dmg,on hit effect and attack speed.Now choose Phantom dancer for more attack speed and crit chanceor Infinity edge for more dmgNow you got all Equip to win, if you got more Gold you can buy One more Infinity edge, or BloodThrister

3.SUMMONER SPELLS
There are the best combination for twitch:+or+and+, You can fix it Other Summoner spells do not fit him

4.RUNES
I Think Twitch need Max Attack damage, nothing else so all runes must be in attack damage. If you got all attack damage runes you got 90% To First blood and good game It gives you like +20Dmg

5.PROS and CONS
PROS
1.Great carry, can kill teams in a matter of seconds
2.Easy Escape with use Ambush
3.One Of Greatest Attack speed Champions
4.Great Dmg dealer.
CONS
1.Loow Hp,Easy to kill
2.Oracle + Wards stop you to get kill and escape with Ambush
3.Can Be CC'ed