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Flash is great because it's versatile and easy to use. It is obviously best for dodging a single ability or getting over walls, etc. It is also great for comboing with abilities such as E or R, though flash combos aren't particularly useful for Sion compared to some other champions.
Ghost is great for more specific reasons and is less versatile in my opinion. The best arguments for ghost are that it is a shorter cooldown, lasts a long time, and it scales with level. It is ideal for extended fights and trades, allowing you to stick to opponants in situations where they would normally outrun you. It is also great for teamfights because it lasts a long time and the duration is extended on takedowns. I find it to be incredibly useful when freezing the enemy minion wave at your tower. Once the enemy comes up to farm, (assuming you are stronger than them) you can throw an E at them and Ghost to run them down and kill them. They have to run all the way back to their tower and can't outrun you.
Overall, I suggest trying them both out and see which you think works best for you. Ghost is a bit more of an aggressive option and will work better with more aggressive builds. Flash is more versatile and safe. There's never a bad game to take flash in. Taking ghost can make you especially vulnerable against certain Junglers who need to land a skill shot on you, like Elise, so you'll have to be more observant of the enemy jungler and react quickly.