LoL Best Vayne Build Guides 2025
Build guides for Vayne on MOBAFire. Find recommended items and runes by high ranked players to learn the best Vayne builds. Create your own champion guide!
Season 11 Builds
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[S11] Tank Killer (Top/Bottom)
[S11] Tank Killer (Top/Bottom)
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Tank
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The Ultimate Vayne Build
The Ultimate Vayne Build
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Hypercarry Vayne ADC (Patch 10.23 -Preseason 11)
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[PRESEASON] Vayne
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Bad Theory Crafting: Support Vayne
Bad Theory Crafting: Support Vayne
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VAYNE PRESEASON 11 GUIDE (VAYNE OTP) PATCH 10.23 (GOLD +)
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27,089,522K Million GOSU NEW HIDDEN ITEM GUIDE !
27,089,522K Million Vayne Unrivaled! League of VAYNE TOP !!
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Magnum Explosion Vayne
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[PRESEASON] MONOVAYNE
Season 10 Guides
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[10.22] In-Depth Vayne Build and Gameplay Guide
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Ultimate Vayne Hard Carry Guide
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Vibin with Vayne
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[ADC] Vayne Guide Patch 10.14
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Vayne-Kenshiro Hokuto late game w madness
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Vayne Guide | Build & Runes | 10.11 Patch [Updated]
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[Top] Vayne, Hypercarry Queen - Full in-depth guide (W.I.P.)
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[S10.10] ADC Vayne, the Night Hunter - Lategame has Arrived
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Vayne As Perfect As Udyr
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