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LoL Best Cassiopeia Build Guides 2025

Build guides for Cassiopeia on MOBAFire. Find recommended items and runes by high ranked players to learn the best Cassiopeia builds. Create your own champion guide!



Season 1 Builds
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Full AP+MP Build

Build by touhouaero updated November 7, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia- The Haunter

Build by PoisonCress updated November 6, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Hey little snake.....WTF?????? : Cassio: Make them RAGEQUIT!

Build by fotispower updated November 6, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Trowin' Snekes White Boey

Build by Crwnprinceherpes updated November 1, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia - I'm goin' to solo Baron!

Build by Dayuum updated October 31, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

SUPEROP

Build by Letsplaysc2 updated October 30, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Endless Mana Legendary

Build by sefoline updated October 29, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Noob cass dominion

Build by Serverbot updated October 19, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassie Build

Build by Xelinor updated October 12, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia Mistress of Poisons

Build by Infuscare updated October 9, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassio mid ownage

Build by Hikaku updated October 9, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

cassiopeia - legendary

Build by murluc124 updated October 1, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassio on each moment

Build by wiewiek updated September 30, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

cassharrass

Build by SaxySam updated September 29, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia - The evil snake woman!

Build by Gurkisch updated September 28, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

How to play High ELO Cassiopeia

Build by BansheesV3il updated September 27, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

JoOGaaBo||Cassiopeia

Build by JoOGaaBo updated September 27, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

OP CASSter

Build by iExcel updated September 24, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Darken's Cassiopeia Compiled

Build by DarkenJade updated September 22, 2011
Rating Pending
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

Cassiopeia

Build by Ikier updated September 7, 2011
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