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Spells:
Ghost
Flash
Ability Order
Death Defied (PASSIVE)
Karthus Passive Ability
Introduction

I personally have found a lot of success with this guide and the only loss I have had with this was a 4v5 (~10 games total at the time). I hope that this guide will help you and your team achieve victory, in the same way in which this guide has worked for me.
NOTE: I will be formatting this guide to make it a lot more appealing but I feel that the community needs a good Dominion Karthus Guide out ASAP, and making this guide look pleasant is not a priority. I will be doing a base guide which I will edit into the complete guide, so please be patient until the guide is complete, and use the resource as it is, until it is finished.
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Here is a summary of my guide as a place-holder while I make the complete guide.
I will explain the runes better in the future, basically use any runes you would for an AP caster.
Rod of Ages more worthwhile. You get MR, Armor, health, and you receive 4% less damage. You also get 4% more AP, and 1% of your max mana in Health Regen. With this build you have over 4k mana which gives you 40 more health-regen per 5 secs. All of these things are a lot more useful in Dominion than a utility tree spec.
Lay Waste and one in
Defile. Then buy
Tear of the Goddess and
Boots as quickly as possible. Then exit the shop and begin spamming
Lay Waste. With your
Tear of the Goddess you should be able to build up an extra 100 mana before the game even begins. For me this takes me from 800 to 900 mana.
Heimerdinger, then you want to cap the Mid Turret, then transition up to Top Tower and help your team.
Rod of Ages,
Sorcerer's Shoes, and
Tear of the Goddess at this stage of the game. During this part of the game, you want to be Defending hard and trying to assist your teammates whenever you can. Also if you have any time idle, you want to be spamming
Lay Waste as much as possible assuming you have the mana for it. You want to get your
Tear of the Goddess/
Archangel's Staff stacks up to 1000 ASAP.
Rod of Ages,
Sorcerer's Shoes,
Archangel's Staff,
Rabadon's Deathcap, and be starting on your second
Rod of Ages (or
Void Staff if the game is going to be ending soon), at this stage of the game. During this part of the game, you want to be Defending hard and trying to assist your teammates whenever you can. Again if you have any time idle, you want to be spamming
Lay Waste as much as possible assuming you have the mana for it. You should have your
Archangel's Staff stacks at 1000 by now.
Summoner Spells
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Runes
I will explain the runes better in the future, basically use any runes you would for an AP caster.
Masteries
Why the 9/21/0?
We take the standard 9 into offense for the AP, CDR, and Spell Pen. The 21 in defense makes all the health you are getting from your
"Pre-Game"
Okay, once you enter the game immediately pick two points in





Early Game
You want to go BOT or MID -> TOP as Karthus. You shouldn't be going Top immediately because you should have someone faster on your team. If you have a good Bot champion on your team such as
Bottom Tower![]()
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Mid -> Top Tower
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Mid Game
This part of the game is quite chaotic and everyone is running around trying to cap towers while defending backdoor pushes. You should have your





Late Game
This part of the game is extremely chaotic, the losing team is desperately trying to get the turret advantage before its too late, and the winning team is trying to hold off the mass pushes while trying to relieve pressure by backdooring. You should have your







Item Build Discussion
You get ![]() ![]() |
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You get Catalyst the Protector next because it helps you stay out on the field and defend longer by giving you health and mana regen every level-up. You pick up ![]() ![]() |
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You want your ![]() ![]() ![]() ![]() ![]() ![]() |
You get ![]() ![]() ![]() |
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You get your ![]() ![]() ![]() |
You want some sort of defensive item that still gives you AP at this point in the game. Basically you can get ![]() ![]() ![]() |
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You get your ![]() ![]() ![]() ![]() ![]() ![]() |
In Conclusion, Karthus is a great champion for Dominion, because of his global ult and great defending capabilities. This Build provides Karthus with a lot of survivability without taking away from his damage at all. This build is great for defending and for Dominion in general, however I am in fact open to suggestions about runes, masteries, summoner spells, or items.
Please leave a comment below with any ideas or suggestions that you have for my guide. Thank you for your time!
Please leave a comment below with any ideas or suggestions that you have for my guide. Thank you for your time!
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