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Your passive for your E as thresh Flay, scales ridiculously and provides so much burst you could pop a country's economic bubble.
"Passive: Thresh deals bonus magic damage on each auto attack. The damage is equal to the number of souls he has collected plus 80/110/140/170/200% of attack damage, based on length of time since last attack."
With the items above you would have 80% crit. You can sell boots late for phantom or something to get the full l00% but I don't normally do that.
Stack this with Statikk Shiv and Rapid Firecannon and you are now able to 1-shot a squishy champ. ADCs in 2017. As you farm you gain AP and Armour, plus extra damage on your E and its passive. You, as an ADC, now have engage, disengage, crowd control, tankiness and burst. You also scale with souls you farm, and as an ADC you should have a lot of farm. You're basically a ranged nasus. Or an AD veigar. Almost as if you were Vayne and Sivir's love child.