Very very hard lane pre 6. Post 6 and on u can kill her if she builds malignance or ludens. However there's a new build where she goes liandries bloodletters riftmaker that makes her very hard to kill in mid game. Focus on baiting/dodging her q and not letting her proc her 3 hit passive.
Ahri
pre 6 just survive. Post 6 you basically just wait for her to q the wave then u ult forward and e+q. When u ult forward click directly to the left or right and u can very consistently dodge her charm.
Akali
Skill matchup. Block her q with your q. Don't get hit by e. Play around her w since it's a really long cd early. This matchup is all about tethering and resource management.
Akshan
Really tough matchup. Focus on staying alive and pinging very effectively when he leaves lane for your team. Best bet here is to max e and go glass cannon so u can set up your jungle for a gank and kill
Ambessa
Skill matchup. Trade around her w and q cds. U can space her out and poke with e+q don't take even trades with her. She has no range.
Anivia
I somehow lose this matchup everytime I play it but most important things about the matchup are your q cancels his r and you can't get hit by his q. If u remember those things u can just murder him on side lane on repeat
Annie
Freelo imo. Just don't get murdered by her at 6. If u can slow the game down and play around her stun you can outscale her very quick
Aurelion Sol
Free Matchup we are thanos against him 1v1. Only problem is u need to snowball and end game quickly or he will reach a point where his abilities cover the whole screen
Azir
I recommend q max. Just don't take 100-0 all ins unless fed and play around your q cd and u should be good.
Brand
who plays this champ. Only matchup I would consider d-shield and second wind in just bc it's so op vs his passive
Cassiopeia
Outscales u 1v1, gets tanky and hard to 1 shot and her w counters u. That said u can beat her in lane. if u dodge her q you have like a 4 second window to trade. The way her damage works if her q misses you it cuts her damage and half and she loses her healing.
Cho'Gath
First strike, dodge q, free scale profit
Corki
**** this champ.
Diana
q max, dodge her q and it's gg. Just don't int the early lane and u win
Ekko
q max, dodge his q and wait till levels 5+ to interact. If he e's onto u hold q until after he lands. I recently learned the hard way that his e blink can fizzle your q damage
Fizz
q max op. If u q and he uses e your q cd is much shorter when u max it. Just don't int early and consider resolve secondary and you're gucci
Galio
Recommend first strike. Don't trade with this champion ever only poke. He is a raidboss. Need to be hyper aware of his roams for yr team and communicate well. Your job vs. him is just to slow the game down
Gangplank
Thanos
Garen
He can never kill u if u don't let him get on u but you can never kill him either. Be careful because he q cleanses slows so you want to use e after his q if he 's running at you
Gragas
Skill matchup. Dodge his q or block it with q. Try not to get bombad or ulted under tower
Hwei
One of the harder control mages. Trade after he uses q on wave post 6, dodge e and you're gonna completely destroy him, get hit by e and you lose
Irelia
gg hope she ints.
Jayce
Very hard. one time I solo killed Full Metal Jayce at level 5 as kassadin though that was fun
K'Sante
e max, first strike, farm. Don't get hit by 3rd q or w. Don't get ulted over a wall
Draven
He ****s you up but if jungle ever comes mid he's a walking sack of gold
Katarina
If they go ap this is free. If they go ad you have to be very careful. You can kill her 6 times but as soon as she gets botrk or kraken she has kill threat. Take short trades and play around her daggers and your cds. Also your q cancels her ult
Kayle
Free scaling just don't int pre 6, kayle is deceptively strong in early all ins. Punish her post 6 by taking short trades when she uses q on minions max e
Kennen
Free scaling just don't int early
Kled
Idk about the new rework but old kled could 100-0 tower dive u level 3 with 0 help from jungle if u messed up.
LeBlanc
Skill matchup but it's very Kassadin favored imo once you learn it. 3-5 points q and press q on her when she jumps in with w or presses q on you. Dodge her e and don't die to ganks and you're golden. Recommend electrocute with resolve for most people
Lissandra
Only worry is gank setup for jungle and inting pre 6. Electrocute with unflinching is really op here. You completely body her 1v1 post 6 if you're not 100 cs down
Kassadin
unplayable matchup kassadin too
OP
Lucian
don't die, build glass clannon, hope he ****s up and punish when he does. Post 6 hold your q for his ulti
Malphite
Free lane just go first strike and 3 points q and malphite legit can't do anything to you
Malzahar
Possibly the easiest matchup in the game 1v1. Kill voidlings. Use q to keep his passive on cd. Contest his push and fistfight him at 6. Only think you have to worry about are his gank setup and dodge his q. His q doubles the duration of his e DOT
Mel
Freelo. Just don't die pre 6 and it's gg. just dodge e and space out your abilities so u don't blow your hole combo into her w. If she ever uses her w you can pretty much just all in her if you know where enemy jgl and support are.
Lux
Just dodge her q and you can't die. Only annoying thing is she just nukes the wave at 6 from 10 screens away. Easy farming matchup though
Naafiri
Actual thanos champ against you. Just farm and get xp. Legit never trade with him. Hope he ****s up.
Nasus
U can unironically solokill this champ pre 6. Just punish him when he uses q on a minon. Don't try to all in him with his ult up max e and he can't play the game
Neeko
Lots of cc and gank setup. Does weird clone ********. Annoying low cd poke. Very sharp matchup it's very easy to int early vs. neeko so don't do that. I will q max this sometime. Focus on playing skillshot dodging simulator then punishing her cooldowns with a trade
Nocturne
Idk if anyone plays this champ mid anymore but it used to be really hard. Infinite sustain instant wave clear and really good roams. He also has a '**** you you're dead' button on his ult if you ever step up too far
Nunu & Willump
Just don't get hit by snowball when he nukes the wave. Post 6 after he snowballs the wave just jump on him and go for a trade. Hold your q for when he ults though or he's just root you into full channel ult and it's cooked
Orianna
Probably the most difficult control mage matchup imo. She has strong autos and low cd reliable burst. Very skill expressive for both matchups. The person who dodges more abilities basically wins. If they don't go phase rush I always like to max e because it's great gank setup against immobile mages
Pantheon
THANOS cannot interact
Qiyana
The good news is most qiyanas are god awful at the champ because it's such a hard champ to play. The bad news is if you're vs. a good qiyana this matchup can be really hard. You're basically relying on her to piss her pants when she tries to combo you
Quinn
Don't die ping out roams and u kill her mid game. Punish her roams by pushing wave. I recently had a game against quinn where I was like 2-3 levels up at 10 minutes bc she just dropped 10 waves mid
Karma
Hard to kill bc of her shield and mantra w and she has good gank setup good waveclear and reliable low cd poke. That being said it's pretty easy to treat this like a farm lane and just not die
Renekton
THANOS cannot interact
Rumble
He can't kill you unless you opt into it for the most part. Just be wary of roams and his all ins early game
Ryze
Went from being a free matchup to a 46% wr matchup for kassadin and idk what happened. Point and click cc is op I guess. Max e, use it for gank setup. Your q actually prevents him from porting on his R which I didn't know until recently
Seraphine
can't kill you but you can kill her, free scaling
Sett
THANOS cannot interact
Sion
He can take plates and push early but I just take first strike and trade on him under the tower. If he ever builds bamis it's free. He takes instant tower aggro bc of bamis if u trade with him and can no longer push plates
Smolder
Kinda annoying early, but you can kill 6-9 if he messes up at all and if especially if jungle comes mid at all.
Swain
dodge e and ult e+q on cd when he uses e and it's free. If he ults just slow him, run away and wait it out.
Sylas
Don't int early. Max q and don't get hit by e2 stun. If you can do that and trade q for w you win this matchup.
Syndra
First strike I take cashback and 2% movement speed so I can get tier 1 boots in the first or second base. After that she can't lane q if u have human movement
Taliyah
don't get hit by he w and ping her roams. She has 0 kill threat on your post 6 unless u get hit by a naked w or it's like a point and click jungler on enemy team
Tristana
Good think is she can't freeze but **** this champ I ban it sometimes
Talon
don't get cheese pre 6. Dodge his w and don't let him proc his passive where 90% of his damage comes from. U can actually take short trade post 6 if he uses w on the wave. Ping out his roams
Tryndamere
THANOS cannot interact
Twisted Fate
Idk low cd point and click cc is really annoying. You beat him 1v1 but his job is very easy. He just needs to waveclear mid and press r on side lanes. It's should be a relatively easy matchup but I lost every game vs. TF recently
Urgot
THANOS cannot interact
Veigar
Might be easier than malz tbh. Just don't over extend if u don't know where jungle is. If you have good movement and ult usage it's really hard for him to play the game vs. you
Vel'Koz
Can't kill you unless you opt into it by ulting forward. Farm it out, you definitely can kill him in lane but it can be very risky to go for all ins early against this champ because he has so much damage if he can land his abilities. You nuke him if you guys are even level 11+
Vex
Actually kind of an annoying matchup. I max q and dodge her e. Her fear mechanic is very good vs. you but you'll eventually outscale her 1v1 pretty hard. I recommend electrocute with resolve here tbh
Viktor
Annoying early lane, annoying poke but very vulnerable to ganks and he gets nuked by you mid late.
Vladimir
Max q and don't let him hit 3rd q. My dark technology is that when I can get ahead vs. him I go malignance>seraphs>Morello and you just murder him on side lane. But you have to be careful building like that bc you become a wet noodle if you mess up with morello
Xerath
See syndra notes. Exact same thing except I will run electrocute in this matchup bc his range is so big. Dodge stun or ult over it
Yasuo
Very sharp Skill matchup. Don't trade with his shield up. Don't take extended trades and don't int early. You can ult over his q3 but it can be hard to time. Do what you can to keep the wave on your side bc he can run you down the lane
Yone
A little bit harder than his brother but more annoying because he's a more useful champ even if he gets behind. Play around his q3, e, and w cd. Do what you can to keep the wave on your side bc he can run you down the lane similar to yasuo
Zac
Idk this is a weird one but he has infinite sustain medium damage and good waveclear. He can **** you up if you overstep.
Zed
Very hard. dodge his q's and don't get low vs. him It's better to get xp and give some minions than let him tower dive you at 6. If you can make it to malignance seraphs zonyhas without the game being in shambles it's playable
Ziggs
Annoying poke but a very vulnerable control mage. Just be careful of roaming too much because he nukes towers
Zilean
free scale, champ is more useless than you early. See BLG vs. Flyquest game 5 2025 MSI
Zoe
Only hard part of the lane is pre 6. Give minions to stay healthy, not int and get xp. Post 6 you are thanos against her and it gets worse for her the longer the game goes. Just don't get hit by bubble. IF you get hit by bubble you lose if you can dodge it she literally can't play against you. Also don't stand inside your minion wave or you will take have your HP bar from her q aoe.
MASTER KASSADIN GUIDE (25.14 UPDATED)
Build Guide By Sirwilliamofyork
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