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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 3 Guides // Patch 25.18
5.2
12
Votes
14
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[Season 14] Sakuritou Challenger Katarina Guide

Guide by Sakuritou updated September 10, 2025
2025, Season 3 Guides // Other Patches
10
240
Votes
15
LoL Champion Galio Build Guide
LoL Champion Galio Build Guide

[25.17] Hexeria's detailed Masters Guide to Galio

Guide by Hexeria updated September 8, 2025
  • In-depth
10
601
Votes
20
LoL Champion Vladimir Build Guide
LoL Champion Vladimir Build Guide

Elite500, UNDISPUTED #1 VLAD PATCH 25.17

Guide by Elite500 updated September 8, 2025
  • In-depth
9.8
2327
Votes
160
LoL Champion Yasuo Build Guide
LoL Champion Yasuo Build Guide

[15.16] Tempest's Challenger Yasuo Guide [In-Depth]

Guide by WayOfTheTempesst updated August 29, 2025
  • In-depth
9.8
171
Votes
8
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

[25.17] Anguishs GrandMasters Akali Mid/Top S15 Guide - Every Matchup/Item/Rune explained!

Guide by Anguish333 updated August 29, 2025
  • In-depth
9.8
2607
Votes
129
LoL Champion Yone Build Guide
LoL Champion Yone Build Guide

[15.17] Tempest's Challenger Yone Guide [In-Depth]

Guide by WayOfTheTempesst updated August 29, 2025
  • In-depth
9.8
832
Votes
54
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.17] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated August 28, 2025
  • In-depth
9.7
180
Votes
15
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[15.17] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.6
68
Votes
7
LoL Champion Aurora Build Guide
LoL Champion Aurora Build Guide

(25.17) ( ADVANCED COMBOS + UPDATED ) AURORA GUIDE : Aurora is one of the best champions to OTP in league ( MOST MASTERY POINTS EUNE )

Guide by AuroraAddict updated August 28, 2025
  • In-depth
9.6
96
Votes
5
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

Guide of an Veigar OTP star zall I Challenger Veigar OTP 1217 LP Peak I

Guide by star zall updated September 8, 2025
  • In-depth
9.5
591
Votes
36
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 16] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated September 8, 2025
  • In-depth
9.5
1989
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.17] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated September 2, 2025
9.5
492
Votes
36
LoL Champion Lissandra Build Guide
LoL Champion Lissandra Build Guide

🍦 [ 25.17 - SEASON 15 - The MIDLANE ICE QUEEN OF DEATH! 🍦

Guide by RezoneVerified updated August 31, 2025
  • In-depth
9.5
987
Votes
77
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

[15.17] Rank 1 Kassadin Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.5
355
Votes
30
LoL Champion Malzahar Build Guide
LoL Champion Malzahar Build Guide

[15.17] Rank 1 Malzahar Complete Guide | By Coach xblademojo

Guide by xblademojo updated August 27, 2025
  • In-depth
9.2
2695
Votes
169
LoL Champion Heimerdinger Build Guide
LoL Champion Heimerdinger Build Guide

🔧[ 25.17 MASTER TIER 10 MILLION MASTERY HEIMERDINGER 🔧 SEASON 16 ]

Guide by RezoneVerified updated September 8, 2025
  • In-depth
9
136
Votes
24
LoL Champion Soraka Build Guide
LoL Champion Soraka Build Guide

Master Mid & Top with Soraka: Tips and Tricks for Dominating the Rift

Guide by Goldenstinger updated September 7, 2025
8.6
482
Votes
39
LoL Champion Orianna Build Guide
LoL Champion Orianna Build Guide

⚡ [SEASON 16 UPDATED!! ] Master Tier Midlane Orianna! THE BALLS HURT ⚡

Guide by RezoneVerified updated September 8, 2025
  • In-depth
8.6
535
Votes
70
LoL Champion Swain Build Guide
LoL Champion Swain Build Guide

[ Patch 25.17 NEW SEASON 15 UPDATED!! ] - SWAIN is the GOD OF MIDLANE PAIN! - 🤯

Guide by RezoneVerified updated September 8, 2025
  • In-depth
8.6
88
Votes
12
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

Ultimate Rogue Assassin Akali Guide [25.17]

Guide by janlon99 updated August 31, 2025
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYunaraYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide