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LoL Best Middle Build Guides 2025

Build guides for Middle champions on MOBAFire. Find recommended items and runes by high ranked players to learn the best Middle builds. Create your own champion guide!



2025, Season 2 Guides // Patch 25.12
10
339
Votes
11
LoL Champion Kayle Build Guide
LoL Champion Kayle Build Guide

Rank 1 EUNE Top 8 EUW I Season 15 Kayle Guide by DesperateNasus Multi-season Challenger

Guide by Desperate Nasus updated June 24, 2025
  • In-depth
  • Stream
9.8
586
Votes
34
LoL Champion Cassiopeia Build Guide
LoL Champion Cassiopeia Build Guide

💀[NEW SEASON 15] CASSIOPEIA - The POISON Queen of Midlane ☠ 💀

Guide by RezoneVerified updated June 25, 2025
  • In-depth
9.8
579
Votes
87
LoL Champion Aatrox Build Guide
LoL Champion Aatrox Build Guide

[15.12] Aatrox Mega Guide 7m MP Master Top 100 worldwide

Guide by Veng Shotz updated June 20, 2025
  • In-depth
9.8
831
Votes
54
LoL Champion Twisted Fate Build Guide
LoL Champion Twisted Fate Build Guide

[25.12] Twisted Fate guide - Grandmaster, Halfhand 🥇

Guide by Halfhand updated June 20, 2025
  • In-depth
9.8
368
Votes
48
LoL Champion Sylas Build Guide
LoL Champion Sylas Build Guide

[25.12]✨ OTP Sylas MID Guide

Guide by angeLoon updated June 13, 2025
9.8
986
Votes
75
LoL Champion Irelia Build Guide
LoL Champion Irelia Build Guide

(25.11) Eriosun's Master Tier Complete Irelia Guide - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
9.7
175
Votes
14
LoL Champion Annie Build Guide
LoL Champion Annie Build Guide

[S15] Rank 1 Annie Complete Guide | By Coach xblademojo

Guide by xblademojo updated June 11, 2025
  • In-depth
9.5
980
Votes
77
LoL Champion Kassadin Build Guide
LoL Champion Kassadin Build Guide

[15.12] Rank 1 Kassadin Complete Guide | By Coach xblademojo

Guide by xblademojo updated June 24, 2025
  • In-depth
9.5
346
Votes
29
LoL Champion Malzahar Build Guide
LoL Champion Malzahar Build Guide

[S15] Rank 1 Malzahar Complete Guide | By Coach xblademojo

Guide by xblademojo updated June 17, 2025
  • In-depth
9.5
165
Votes
8
LoL Champion Akali Build Guide
LoL Champion Akali Build Guide

Anguishs GrandMasters Akali Mid/Top S15 Guide Patch [15.12] - Every Matchup/Item/Rune explained!

Guide by Anguish333 updated June 16, 2025
  • In-depth
9.5
190
Votes
17
LoL Champion Zoe Build Guide
LoL Champion Zoe Build Guide

[25.12] clipbot's Zoe guide for beginners

Guide by Aegox updated June 12, 2025
  • In-depth
9.2
410
Votes
43
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

(25.11) Eriosun's Complete Master Katarina Guide - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
9.2
1980
Votes
128
LoL Champion Katarina Build Guide
LoL Champion Katarina Build Guide

[25.12] Nyro Challenger Katarina Build Guide

Guide by Nyrolol updated June 12, 2025
8.9
266
Votes
47
LoL Champion Ekko Build Guide
LoL Champion Ekko Build Guide

Power leon's guide for ekko players in mid lane

Guide by leonidas44 updated June 21, 2025
8.9
90
Votes
11
LoL Champion Qiyana Build Guide
LoL Champion Qiyana Build Guide

(25.11) Eriosun's Qiyana Midlane Master Tier Guide, Rank 1 on the 24 Sisters - Season 15 [UPDATED]

Guide by Eriosunx updated June 12, 2025
  • In-depth
8.9
602
Votes
35
LoL Champion Azir Build Guide
LoL Champion Azir Build Guide

[Season 15] BodyThoseFools' Challenger Azir Guide [In-depth] (10,000,000+ Mastery Points) (Beat Faker)

Guide by Body Those Fools updated June 11, 2025
  • In-depth
8.7
33
Votes
10
LoL Champion Kai'Sa Build Guide
LoL Champion Kai'Sa Build Guide

[25.12] LOADING SCREEN AP MID POKE KAISA GUIDE protein shakes are food

Guide by PalestinianLuck updated June 14, 2025
  • In-depth
8.6
161
Votes
19
LoL Champion Veigar Build Guide
LoL Champion Veigar Build Guide

Veigar - Carry Alone

Guide by ReapeRGP updated June 24, 2025
8.5
8
Votes
0
LoL Champion Samira Build Guide
LoL Champion Samira Build Guide

[25.13] King Branco's Samira MID LANE Guide - Ultimate Guide From A Samira Mid OTP

Guide by KingBranco updated June 25, 2025
  • In-depth
8.5
11
Votes
1
LoL Champion Mel Build Guide
LoL Champion Mel Build Guide

Evandabank's Grandmaster Mel Midlane Guide

Guide by Evandabank updated June 23, 2025
  • In-depth
  • Featured
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AatroxAhriAkaliAkshanAlistarAmbessaAmumuAniviaAnnieApheliosAsheAurelion SolAuroraAzirBardBel'VethBlitzcrankBrandBraumBriarCaitlynCamilleCassiopeiaCho'GathCorkiDariusDianaDr. MundoDravenEkkoEliseEvelynnEzrealFiddlesticksFioraFizzGalioGangplankGarenGnarGragasGravesGwenHecarimHeimerdingerHweiIllaoiIreliaIvernJannaJarvan IVJaxJayceJhinJinxK'SanteKai'SaKalistaKarmaKarthusKassadinKatarinaKayleKaynKennenKha'ZixKindredKledKog'MawLeBlancLee SinLeonaLilliaLissandraLucianLuluLuxMalphiteMalzaharMaokaiMaster YiMelMilioMiss FortuneMordekaiserMorganaNaafiriNamiNasusNautilusNeekoNidaleeNilahNocturneNunu & WillumpOlafOriannaOrnnPantheonPoppyPykeQiyanaQuinnRakanRammusRek'SaiRellRenata GlascRenektonRengarRivenRumbleRyzeSamiraSejuaniSennaSeraphineSettShacoShenShyvanaSingedSionSivirSkarnerSmolderSonaSorakaSwainSylasSyndraTahm KenchTaliyahTalonTaricTeemoThreshTristanaTrundleTryndamereTwisted FateTwitchUdyrUrgotVarusVayneVeigarVel'KozVexViViegoViktorVladimirVolibearWarwickWukongXayahXerathXin ZhaoYasuoYoneYorickYuumiZacZedZeriZiggsZileanZoeZyra
Teamfight Tactics Guide