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Ahri isn't too hard to lane against but once you get into high elo, they won't just throw out their charms randomly as they do in low elo. Good Ahri's will save their charm for when you go for a full engage, and in that aspect Ahri wins in overall damage. Her ult also works really well agaist yours as she has 3 dashes to get away from whatever you may throw at her. This is mostly a skill matchup.
Katarina
Zed has a pretty high advantage over Kat in my opinion. This can also be considered a skill matchup (honestly most lanes are) but Zed can win this lane pretty easily as long you play carefully. Never ult her if her ult and shunpo are both up. She will outdmg you at early levels. Some Kats like myself will rush a zhonyas against a Zed so keep an eye on her items too. Still think Zed has the advantage if you use your ult to dodge most of hers.
Karthus
Easiest lane for Zed in the game. Can't really lose this. Deny him as much as possible.
Talon
Really underrated strong mid laner in this meta. Is sometimes called a better Zed but imo, Zed has better potential than Talon has. Also much more fun ;). Around the time you go back at level 6, make sure to pick up a pink ward. Any decent Talon will ult as soon as you do to deny your dmg onto him. Make sure you place your pink as soon as you see him ult, or even do it preemptively because he most likely immediately ult. If you don't get a pink or a sweeper to counter his ult, Talon could easily outdmg and kill you. Talon is also a much better roamer who can easily walk up and kill your bot lane so make sure to let your team know he's missing.
Kassadin
Easy lane for Zed. His Q shield does literally nothing for him and even if he ult away from your ult, you can W after him and do enough dmg for him to die from the pop before his ult is up again. Again, make sure your team knows when he's missing. Kassadin is a great roamer and if given the chance will snowball off other lanes.
Lux
Not a popular mid laner recently but I've seen her quite often and it's a fun matchup. Zed wins this hard too. Make sure to try to predict and dodge her bindings with W or R because if you pull it off, theres no way she'll be able to escape without burning flash. Even then, if your W is up you an catch up easily. Lux relies entirely on her lining up her skillshots together. You dodge the binding and the rest won't affect you much at all.
Kayle
Hugest Zed counter. Ridiculous matchup. Look to either farm or roam to other lanes. There's no way you'll win this matchup as long as the Kayle isn't mechanically deficient. Zed doesn't necessarily lose this matchup either. It's just not a matchup he can win.
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