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Nautilus Build Guide by j4ss

Optimal Nautilus for Midlane - Patch 25.22

Updated on November 6, 2025

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League of Legends Build Guide Author j4ss

Build Guide By j4ss

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1,594 Views

0 Comments League of Legends Build Guide Author j4ss

Nautilus Build Guide By j4ss Updated on November 6, 2025

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Recommended Items

Sorcerer's Shoes

Hollow Radiance

Fimbulwinter

Thornmail

Dead Man's Plate

Jak'Sho, The Protean

Runes: Aggro Setup

1 2 3 4

Resolve

Aftershock

Shield Bash

Bone Plating

Revitalize

Sorcery

Nimbus Cloak

Scorch

Bonus:

+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+65 Base Health

Resolve

Aftershock

Shield Bash

Second Wind

Revitalize

Inspiration

Biscuit Delivery

Cosmic Insight

Bonus:

+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+10-180 Bonus Health

Resolve

Aftershock

Demolish

Bone Plating

Revitalize

Domination

Relentless Hunter

Cheap Shot

Bonus:

+10% Attack Speed
+9 Adaptive (5.4 AD or 9 AP)
+65 Base Health

Resolve

Aftershock

Demolish

Conditioning

Overgrowth

Sorcery

Absolute Focus

Gathering Storm

Bonus:

+10% Attack Speed
+10-180 Bonus Health
+65 Base Health

Spells:

1 2

Standard Spells

Flash

Ignite

Side Lane Nautilus

Flash

Teleport

Items

Standard Build

Sorcerer's Shoes

Hollow Radiance

Fimbulwinter

Thornmail

Dead Man's Plate

Jak'Sho, The Protean

Standard Nautilus (Read Notes)

Starter Items

Doran's Ring

Health Potion

First Buys

Sorcerer's Shoes

Dark Seal

Tear of the Goddess

Magic Resistance Focus

Hollow Radiance

Fimbulwinter

Kaenic Rookern

Abyssal Mask

Unending Despair

Armor Focus

Sunfire Aegis

Fimbulwinter

Thornmail

Dead Man's Plate

Unending Despair

Roaming Nautilus (Read Notes)

Starter Items

Dark Seal

Refillable Potion

First Buys

Symbiotic Soles

Doran's Ring

Bami's Cinder

Magic Resistance Focus

Hextech Rocketbelt

Hollow Radiance

Unending Despair

Abyssal Mask

Jak'Sho, The Protean

Armor Focus

Hextech Rocketbelt

Sunfire Aegis

Unending Despair

Thornmail

Jak'Sho, The Protean

Passive Nautilus (Read Notes)

Starter Items

Doran's Shield

Health Potion

First Buys

Plated Steelcaps

Mercury's Treads

Tear of the Goddess

Magic Resistance Focus

Hollow Radiance

Fimbulwinter

Kaenic Rookern

Abyssal Mask

Unending Despair

Armor Focus

Sunfire Aegis

Fimbulwinter

Thornmail

Dead Man's Plate

Unending Despair

Ability Order E > Q > W

Threats & Synergies

Threats

Synergies

Extreme Major Even Minor Tiny

Show All

None Low Ok Strong Ideal

Extreme Threats

Ideal Synergies

Ahri

Minor

You outsustain her harass, you can rush merc boots and basically win lane for free.

Akali

Minor

She is annoying but still melee, your W and E waves reveals her position in the shadow so you can hook her easily. R reveals her completely. Don't over extend if she has conqueror and don't let her roam. follow her on sidelane to avoid her to come back.

Anivia

Even

Annoying poke and passive but easily gankable, no mobility, she have to execute her champion a lot better than you to win side lane and not die.

Aurelion Sol

Major

Very big scaling and annoying poke, but his kit makes it easy for you to engage him, ALWAYS focus him on team fight, even if he is behind, he can easily come back if he farm free kills in team fights.

Aurora

Even

Very annoying damage, but your setups can outsustain it. Her R can avoid your R, so use it wisely. She can never burst you and is very squishy if she goes full damage.

Azir

Minor

Easy lane, his poke is annoying but not enough, just be careful with his scaling.

Cassiopeia

Even

Annoying lane, very big scaling but no mobility, your point-and-click ultimate have to always be reserved to her, just like aurelion sol, focus her every single fight and don't let her gets strong. force mid game fights.

Diana

Minor

Melee, her E is a death sentence to her, don't let her roam and insta follow her, just be careful with fake roamings, alone she is a minion, but can do a lot of damage with setup. Focus in hard pushing and punishing her farms. you can deny cannon minion with Q if you hook her out of turret range.

Ekko

Minor

Same as Diana, melee assassin, your MR items are great and you always force them to use their important cooldowns, so punish them in lane and share your advantage with your team doing objectives and roamings.

Fizz

Even

Annoying assassin, his E makes it very annoying to land ultis, but besides that, stack MR and you'll never be solo killed. Follow his roamings and be careful with fake ones.

Galio

Tiny

No threat, you do everything he does but better. Hard to kill since he builds tons of health, just perma push waves and follow his roamings. Focus in team fights and objectives.

Hwei

Minor

Annoying poke but easy to punish.

Irelia

Even

Don't over extend fights and play around her E, play close to your turret and buffer her E with your hook on walls to escape damage. Rush plated steelcaps, build a lot of armor and Thornmail second after sunfire. Play with your jungle because she is free kill in skirmishes and 2v2s.

Kassadin

Minor

Free lane but he can scale a lot. Focus in solo killing him or perma pushing and roaming. Secure atakhan and early drakes to mitigate his late game.

LeBlanc

Minor

Annoying but she can't kill you, you can Q when she W's if you have decent reflexes and your R will follow her even if she turns invisible for the passive or goes back with W. She can't punish you sidelane and is easy target when team fighting.

Lissandra

Even

Annoying poke and roaming, hard to kill because of ult. Rush Merc and force her cooldowns and spells. Follow her roamings and follow her in sidelanes. Sidelaning setup is good to force her to follow you, she can't kill you but if she tries you can easily win.

Lux

Minor

Annoying poke but easy kill. Immoble mages are easy to deal if you outsustain their damage.

Malzahar

Even

Annoying poke and clear wave, focus in outsustain his damage and do a lot of roams and early objectives.

Mel

Major

She can counter your R and Q with her W, have a lot of poke, so focus in always clear waves and leaving lane with tempo. Symbiotic Soles + Sustain setup is great here. Later on you can easily punish her if she wastes her W.

Naafiri

Minor

Melee AD assassin. Rush plated steelcaps, bami sinder and Bramble vest and will beat him most of the time. Side lane is easy and he is easy to catch in teamfights, specially after he wastes his W.

Orianna

Minor

Annoying poke but extremely squishy, free kill if you keep wave close to your turret, stays with your minions to force her to push when poking. Setup ganks on her and secure early objectives.

Veigar

Major

Annoying poke and crazy scaling. You win lane but late game you can do nothing. Focus in objectives and making your team strong.

Vex

Minor

Annoying poke but easy kill. She can never burst you, so you win most of trades.

Sylas

Even

Annoying sustain, but you win most trades early on. bramble vest rush and then hollow radiance. your ult is very good for him so be careful.

Yasuo

Minor

Start trades with passive and finish with Q+E for both avoid over extended trades or to chase. Not hooking him immediatly can bait him into using his W too early, punish that. Plated steelcap rush and start sunfire with Chain Vest. he is very easy to punish with ganks, so call your jungler to bait his attempts to trade and forces his windwall. having your defensive items will allow you to save you important cooldowns.

Yone

Minor

No windwall, but better kit for trades. Rush plated and chain vest, and bait his 3rd Q. Best you can do in this game is setup ganks, roaming and punishing his agressive plays. Force early objectives and secure atakhan.

Zed

Minor

Stack armor and will be very hard for him to kill you, your R will follow him through all of his blinks, just don't let him R before getting hit, because if it lands, is free kill.

Ziggs

Even

Annoying poke but free kill. Go sustain setup and setup ganks. You only need 2 or 3 interactions to solo kill him, so single nullmagic mantle into sorcerer shoes will be great to at least force his spells.