Ryze

Aurelion Sol

Gragas

Kassadin

Heimerdinger

Heimer is usually very good at pushing people in and gaining large leads through cs alone. Orianna however does not struggle at all in dealing with him. You can use your range to safely remove his towers faster than he can replace them by simply using Q. I would not reccomend using Q->W to take them out though as this will make you run out of mana very quickly. Without towers up, this champion really struggle. Especially if you can push him under his own turret!

Karthus

Although he does do lots of damage, his skillshots are easy to dodge and he has no cc. I find this matchup quite easy as long as you can outthink the Karthus and dodge his Q spam. You should be able to bully him early, and burst him out nearly instantly mid and late game. He cant do much against a banshee veil, but you can just go full damage on him and be much more impactful. Recommend: Barrier and Dmg Build

Lissandra

I used to main this champion and she is in a very weak place right now. She is practically unplayable, but if you are up against one, celebrate. You outrange her easily and as long as you take cleanse, she doesn't even have kill pressure on you. Don't waste your time with defensive items and go full damage to crush her all game. Recommend: Cleanse and Dmg Build

Veigar

Veigar has a really strong late game due to his stacking AP, but it usually never gets to the point where he actually outscales an Orianna. You can harass him early since his W and Q are not that hard to dodge. Lots of people take barrier, but i find cleanse really counter Veigar, since 9 times out of 10, if i die to him it was because i got stunned in his cage and he landed a full combo on me. If you do get caught to close, just walk into the cage and cleanse out instantly to escape whatever damage he was going to land on you. Recommend Cleanse and Dmg Build with a Banshee Veil as item 4-6 so that if he does get that the insane level, you have a shield to block high damage spells. Recommend Cleanse and Dmg Build Note: If he goes tank, opt into Liandry's Torment and Void Staff.

Anivia

Annie

Cassiopeia

Corki

Karma

Talon

Viktor

Zoe

Fiddlesticks

Gangplank

Kayle

Morgana

Zilean

Akali

Brand

Ekko

Jayce

Lucian

Taliyah

Swain

Diana

Malzahar

Twisted Fate

Vladimir

Fizz

Lux

LeBlanc

Ziggs

Ahri

Galio

Katarina

Syndra

Vel'Koz

Yasuo

Zed

Xerath