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Runes:
Spells:
Flash
Ignite
Items
Ability Order
Darkness Rise (PASSIVE)
Mordekaiser Passive Ability
Threats & Synergies
Draven
He is probably the hardest matchup on Botlane. He can do massive Dmg and can burst you down very quickly. The best option against him is a Blitzcrank Support. Once your Supp hooked him you guys must use all of your abilities to quickly burst him down. Most of the times a Blitzcrank ULT and Mordekaiser W Combo can do the trick.
Introduction

As a starting item I suggest you to buy a Dark Seal since it makes your early healing from potions stronger, and it will stack up with every kills you get, giving you more AP. Don't forget to buy some potions as well! For your first ability, you have to start with W first. It's great for filling up your passive faster and also deals plenty of DMG if someone gets inside it's area. One more cool thing about your W is that its also gives you healing once it's reactivated and caused DMG to an enemy Champion or minions, moreover you can put the W on any friendly units wich is very effective if your jungler ganks and jumps on your opponent. For the second ability you max Q since it enpowers your auto attacks especially the 3rd. It can deal tons of Dmg and also good as an Executional move. Finally max your E wich is very good for poking your opponent from a distance, and it also fills up your passive just like all of your abilities.
For first item grab a Relic Sield. (Yes support item but you will need it in early game) There will be times when the enemy will laugh at you saying "Two supps wtf??" but don't give a damn about them. For first ability max W just like in Top and Mid, but for second ability max E to make your pokes much more stronger. You are against ranged champs so you will need it, and last max your Q.
As about supports your best option is Blitzcrank. He is good to pull your enemies close to you so you can just put your W on Blitz. From that moment all you guys need to do is just to burst the victim down with everything you got. One more very good supp for Morde is Ekko. His slow and stun is a huge advantage and since he can jump on the enemies your W can cause even more destruction if you put it on Ekko before he jumps in.
Here is a little example how it works: (Yes it's made with the old rune system but the tactic is the same)
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